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Found 24 with Last Name = 'fadda' and Initial = 'mb'
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50327889(5,5'-methylenebis(2-hydroxybenzaldehyde) | CHEMBL1...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of mushroom tyrosinase by Lineweaver-Burke double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataKi:  1.89E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Affinity DataIC50:  980nMAssay Description:Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  8.33E+3nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50327889(5,5'-methylenebis(2-hydroxybenzaldehyde) | CHEMBL1...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50327893(5,5'-methylenebis(2,4-dihydroxybenzaldehyde) | CHE...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50327891(5,5'-methylenebis(2-hydroxy-4-methoxybenzaldehyde)...)
Affinity DataIC50:  1.17E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344062(6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...)
Affinity DataIC50:  2.15E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344060(6-Bromo-8-hydroxy-3-phenylcoumarin | CHEMBL1777847)
Affinity DataIC50:  3.02E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50174558(7-hydroxy-2H-1-benzopyran-2-one | 7-hydroxy-2H-chr...)
Affinity DataIC50:  4.20E+5nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50327892(5,5'-methylenebis(2,3-dihydroxybenzaldehyde) | CHE...)
Affinity DataIC50:  5.23E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50327890(5,5'-methylenebis(2-hydroxy-3-methoxybenzaldehyde)...)
Affinity DataIC50:  6.95E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50139367(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Affinity DataIC50:  8.33E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344061(8-hydroxy-3-(4'-hydroxy)phenylcoumarin | CHEMBL177...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344058(6-Bromo-8-methoxy-3-(4'-methoxyphenyl)coumarin | C...)
Affinity DataIC50:  1.36E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM26189(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)
Affinity DataIC50:  1.44E+6nMAssay Description:Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344055(8-Ethoxy-3-phenylcoumarin | CHEMBL1777843)
Affinity DataIC50:  2.07E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  3.68E+6nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344059(8-Hydroxy-3-phenylcoumarin | CHEMBL1777846)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344056(6-Bromo-8-methoxy-3-phenylcoumarin | CHEMBL1777814)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Universit£

Curated by ChEMBL
LigandPNGBDBM50344057(8-Ethoxy-3-(4'-methoxyphenyl)coumarin | CHEMBL1777...)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50176525(7-hydroxy-3-(3',5'-dihydroxyphenyl)coumarin | CHEM...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50096003(7-Hydroxy-3-phenyl-chromen-2-one | 7-hydroxy-3-phe...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed