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Found 83 with Last Name = 'faucher' and Initial = 'am'
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataKi:  2.00E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137910(CHEMBL434551 | [3'-(naphthalene-1-yl-methylcarbamo...)
Affinity DataIC50:  4.30nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137910(CHEMBL434551 | [3'-(naphthalene-1-yl-methylcarbamo...)
Affinity DataIC50:  4.30nMAssay Description:Binding affinity for human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137889(CHEMBL176784 | [3'-(1-(R)-naphthalene-1-yl-ethylca...)
Affinity DataIC50:  4.5nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137901(CHEMBL175099 | [3'-(2,3-dimethyl-benzylcarbamoyl)-...)
Affinity DataIC50:  9.20nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137919(CHEMBL174279 | [3'-((S)-Indan-1-ylcarbamoylmethyl)...)
Affinity DataIC50:  20nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137899(CHEMBL175280 | [3'-(3-methyl-benzylcarbamoyl)-biph...)
Affinity DataIC50:  27nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011004(CHEMBL3259893)
Affinity DataIC50:  28nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137891(CHEMBL368080 | [3'-(2-methyl-benzylcarbamoyl)-biph...)
Affinity DataIC50:  32nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011132(ALLINI-1 | CHEMBL3259891)
Affinity DataIC50:  40nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137925(CHEMBL368100 | [3'-((R)-1-Phenyl-ethylcarbamoyl)-b...)
Affinity DataIC50:  43nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011131(CHEMBL3259890)
Affinity DataIC50:  77nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137928(CHEMBL172893 | {3'-[((S)-1-Phenyl-ethylcarbamoyl)-...)
Affinity DataIC50:  87nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137921((3'-Benzylcarbamoyl-biphenyl-4-sulfonyl)-acetic ac...)
Affinity DataIC50:  87nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137897((3'-Phenylcarbamoylmethyl-biphenyl-4-sulfonyl)-ace...)
Affinity DataIC50:  110nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137917((4'-Phenylcarbamoylmethyl-biphenyl-4-sulfonyl)-ace...)
Affinity DataIC50:  160nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011044(CHEMBL3259887)
Affinity DataIC50:  270nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137883(CHEMBL368567 | [3'-(Benzylcarbamoyl-methyl)-biphen...)
Affinity DataIC50:  300nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011130(CHEMBL3259889)
Affinity DataIC50:  310nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137886(CHEMBL175036 | {3'-[((R)-1-Phenyl-ethylcarbamoyl)-...)
Affinity DataIC50:  320nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137898((4'-Benzylcarbamoylmethyl-biphenyl-4-sulfonyl)-ace...)
Affinity DataIC50:  340nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011043(CHEMBL3259886)
Affinity DataIC50:  350nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93213(Benzimidazole Inhibitor, 6)
Affinity DataIC50:  350nM Kd:  500nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137924((3'-Phenylcarbamoyl-biphenyl-4-sulfonyl)-acetic ac...)
Affinity DataIC50:  420nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137915((4'-Benzylcarbamoyl-biphenyl-4-sulfonyl)-acetic ac...)
Affinity DataIC50:  510nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137895(4'-Nitromethanesulfonyl-biphenyl-3-carboxylic acid...)
Affinity DataIC50:  630nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93212(Benzimidazole Inhibitor, 5)
Affinity DataIC50:  670nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137884((1,1-Difluoro-2-{3'-[(naphthalen-1-ylmethyl)-carba...)
Affinity DataIC50:  740nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93214(Benzodiazepine Inhibitor, 7)
Affinity DataIC50:  890nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137927((4'-Dibenzylcarbamoyl-biphenyl-4-sulfonyl)-acetic ...)
Affinity DataIC50:  1.10E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93209(Benzimidazole Inhibitor, 2)
Affinity DataIC50:  1.20E+3nM Kd:  4.30E+3nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93211(Benzimidazole Inhibitor, 4)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137916((4'-Phenylcarbamoyl-biphenyl-4-sulfonyl)-acetic ac...)
Affinity DataIC50:  1.30E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137890((4'-Methoxy-biphenyl-4-sulfonyl)-acetic acid | CHE...)
Affinity DataIC50:  1.30E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137908((4-Benzo[1,3]dioxol-5-yl-benzenesulfonyl)-acetic a...)
Affinity DataIC50:  1.30E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93210(Benzimidazole Inhibitor, 3)
Affinity DataIC50:  1.40E+3nM Kd:  8.00E+3nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137904(CHEMBL367131 | [3'-((S)-1-Phenyl-ethylcarbamoyl)-b...)
Affinity DataIC50:  1.70E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137909(CHEMBL439656 | {4'-[(2-Acetylamino-ethylcarbamoyl)...)
Affinity DataIC50:  1.90E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50:  2.00E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011133(CHEMBL3259892)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011129(CHEMBL3259888)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137882(CHEMBL368466 | [4'-(Piperidine-1-carbonyl)-bipheny...)
Affinity DataIC50:  3.30E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137922((3'-Methoxy-biphenyl-4-sulfonyl)-acetic acid | CHE...)
Affinity DataIC50:  4.00E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137923((4'-Methyl-phenylcarbamoyl-biphenyl-4-sulfonyl)-ac...)
Affinity DataIC50:  4.80E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011014(CHEMBL3259885)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137931((4-Naphthalen-1-yl-benzenesulfonyl)-acetic acid | ...)
Affinity DataIC50:  5.40E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)

LigandPNGBDBM93208(Benzimidazole Inhibitor, 1)
Affinity DataIC50:  6.10E+3nM Kd:  4.30E+4nMAssay Description:In vitro capsid assembly assay (CAA) was used in a HTS to identify potential inhibitors of capsid assembly. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137911((Biphenyl-4-sulfonyl)-fluoro-acetic acid | CHEMBL1...)
Affinity DataIC50:  6.50E+3nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50011013(CHEMBL1422607)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of HIV1 integrase by LTR cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein E1(Human papillomavirus type 11)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50137905(2-(Biphenyl-4-sulfonyl)-propionic acid | CHEMBL175...)
Affinity DataIC50:  1.70E+4nMAssay Description:Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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