TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 5.70E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 3.50E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 4.00E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:compounds were evaluated for inhibitory activity against human Tachykinin receptor 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro functional efficacy as increased cAMP in chinese hamster ovary (CHO) cells expressing human beta-3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity was evaluated on chinese hamster ovary (CHO) cells expressing the cloned human beta-3 adrenergic receptor in the presence of [125I]-...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair