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Found 45 with Last Name = 'feigelson' and Initial = 'gb'
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099184((2S,5R,6R)-6-[1-(4-Amino-phenyl)-1H-[1,2,3]triazol...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099190((2S,5R,6R)-6-[1-(4-Hydroxy-phenyl)-1H-[1,2,3]triaz...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099192((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-phenyl-1...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099184((2S,5R,6R)-6-[1-(4-Amino-phenyl)-1H-[1,2,3]triazol...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099186((2S,5S)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099193((2S,5R,6R)-6-[1-(4-Fluoro-phenyl)-1H-[1,2,3]triazo...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099184((2S,5R,6R)-6-[1-(4-Amino-phenyl)-1H-[1,2,3]triazol...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099190((2S,5R,6R)-6-[1-(4-Hydroxy-phenyl)-1H-[1,2,3]triaz...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099190((2S,5R,6R)-6-[1-(4-Hydroxy-phenyl)-1H-[1,2,3]triaz...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099186((2S,5S)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50:  2.80E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099188((2S,5S)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099193((2S,5R,6R)-6-[1-(4-Fluoro-phenyl)-1H-[1,2,3]triazo...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099191((2S,5S)-6-((E)-3-Cyano-allyl)-3,3-dimethyl-4,4,7-t...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099192((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-phenyl-1...)
Affinity DataIC50:  3.40E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099193((2S,5R,6R)-6-[1-(4-Fluoro-phenyl)-1H-[1,2,3]triazo...)
Affinity DataIC50:  4.10E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50:  5.20E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099188((2S,5S)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  6.50E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099194((2S,5R,6R)-6-{1-[2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  6.60E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50:  7.90E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  8.40E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099189((2S,5R)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50:  8.60E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099196((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-but...)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099187((2S,5R)-6-[(E)-3-(Methoxy-methyl-carbamoyl)-allyl]...)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099194((2S,5R,6R)-6-{1-[2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099187((2S,5R)-6-[(E)-3-(Methoxy-methyl-carbamoyl)-allyl]...)
Affinity DataIC50:  1.70E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099196((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-but...)
Affinity DataIC50:  1.70E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099191((2S,5S)-6-((E)-3-Cyano-allyl)-3,3-dimethyl-4,4,7-t...)
Affinity DataIC50:  2.40E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099194((2S,5R,6R)-6-{1-[2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  2.40E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099189((2S,5R)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50:  2.90E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099188((2S,5S)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  4.00E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  4.80E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099186((2S,5S)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50:  6.40E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)
Affinity DataIC50:  6.60E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  7.10E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099192((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-phenyl-1...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099189((2S,5R)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099196((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-but...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099191((2S,5S)-6-((E)-3-Cyano-allyl)-3,3-dimethyl-4,4,7-t...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099187((2S,5R)-6-[(E)-3-(Methoxy-methyl-carbamoyl)-allyl]...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed