Affinity DataKi: 0.0800nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.1kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -49.7kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.3kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -48.8kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nM ΔG°: -48.5kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.0kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 44nM ΔG°: -41.6kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -40.8kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibitory activity of the compound was evaluated against cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 77nM ΔG°: -40.2kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 140nM ΔG°: -38.7kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
Affinity DataKi: 150nM ΔG°: -38.6kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 180nM ΔG°: -38.1kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair