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Found 101 with Last Name = 'finck' and Initial = 'bn'
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50391056(CHEMBL2088421)
Affinity DataIC50:  0.280nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50099491(2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)...)
Affinity DataIC50:  0.460nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50391057(CHEMBL2088422)
Affinity DataIC50:  0.590nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50099489(2-(4-{2-[1-(4-Cyclohexyl-butyl)-3-(2-methoxy-pheny...)
Affinity DataIC50:  1.90nMAssay Description:Agonist activity at PPARalpha-LBD expressed in HEK293 cells co-expressing GAL4-DBD after 16 to 19 hrs by beta lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609069(CHEMBL5281274)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609070(CHEMBL5273108)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609025(CHEMBL5270645)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609024(CHEMBL5289009)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609023(CHEMBL5268548)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609021(CHEMBL5275000)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609020(CHEMBL5266567)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50609022(CHEMBL5267052)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609012(CHEMBL5271527)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609013(CHEMBL5279682)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609014(CHEMBL5272555)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609015(CHEMBL5283322)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609016(CHEMBL5287066)
Affinity DataEC50:  5.70E+3nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
Ligand InfoPDB
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609017(CHEMBL5284954)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609018(CHEMBL5269689)
Affinity DataEC50:  9.70E+3nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetRNA-binding protein FXR2(Homo sapiens)TBA
LigandPNGBDBM50185708(CHEMBL3822464)
Affinity DataEC50:  0.75nMAssay Description:Agonist activity at FXR2 in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRNA-binding protein FXR2(Homo sapiens)TBA
LigandPNGBDBM50609019(CHEMBL5267458)
Affinity DataEC50:  0.350nMAssay Description:Agonist activity at FXR2 in human HepG2 cellsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609026(CHEMBL5266939)
Affinity DataEC50:  12nMAssay Description:Agonist activity at FXR in HEK293 cellsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609020(CHEMBL5266567)
Affinity DataEC50: <30nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609021(CHEMBL5275000)
Affinity DataEC50:  34nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609022(CHEMBL5267052)
Affinity DataEC50:  17nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609023(CHEMBL5268548)
Affinity DataEC50:  10nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609024(CHEMBL5289009)
Affinity DataEC50:  5nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609025(CHEMBL5270645)
Affinity DataEC50:  23nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609027(CHEMBL5270341)
Affinity DataEC50:  2nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609028(CHEMBL5279195)
Affinity DataEC50:  21nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609029(CHEMBL5276532)
Affinity DataEC50:  13nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609030(CHEMBL5281263)
Affinity DataEC50:  10nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609031(CHEMBL5268294)
Affinity DataEC50: <500nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609032(CHEMBL5271645)
Affinity DataEC50: <500nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609026(CHEMBL5266939)
Affinity DataEC50:  12nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609033(CHEMBL5285848)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609034(CHEMBL5282568)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609035(CHEMBL5279380)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609036(CHEMBL5267810)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609037(CHEMBL5266846)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609038(CHEMBL5277834)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609039(CHEMBL5282580)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609040(CHEMBL5288343)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609041(CHEMBL5268282)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609042(CHEMBL5266200)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609043(CHEMBL5290473)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM16111(2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...)
Affinity DataEC50:  450nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataEC50:  20nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
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