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Found 250 with Last Name = 'gómez' and Initial = 'e'
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprine Y-HCl | (+/-)-huprineY hydrochloride...)
Affinity DataKi:  0.0330nMAssay Description:Binding affinity to human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Instituto PolitéCnico Nacional 2508

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Instituto PolitéCnico Nacional 2508

Curated by ChEMBL
LigandPNGBDBM50323914(CHEMBL1213786 | Tamoxifen butyl bromide)
Affinity DataKi:  13.0nMAssay Description:Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Instituto PolitéCnico Nacional 2508

Curated by ChEMBL
LigandPNGBDBM50323912(CHEMBL1213784 | Tamoxifen ethyl bromide)
Affinity DataKi:  13.7nMAssay Description:Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Instituto PolitéCnico Nacional 2508

Curated by ChEMBL
LigandPNGBDBM50323913(CHEMBL1213785 | Tamoxifen isopropyl bromide)
Affinity DataKi:  25.4nMAssay Description:Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Instituto PolitéCnico Nacional 2508

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataKi:  31.2nMAssay Description:Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Instituto PolitéCnico Nacional 2508

Curated by ChEMBL
LigandPNGBDBM50323911(CHEMBL1213783 | Tamoxifen methyl iodide)
Affinity DataKi:  46.3nMAssay Description:Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356004(CHEMBL1911339)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352565(CHEMBL1825149)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352566(CHEMBL1825148 | US8772288, 23)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356003(CHEMBL1911338)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348312(CHEMBL1800222 | US8772288, 12)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356002(CHEMBL1911337)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprine Y-HCl | (+/-)-huprineY hydrochloride...)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352572(CHEMBL1825157 | US8772288, 51)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348323(CHEMBL1800912)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355999(CHEMBL1911334)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352570(CHEMBL1825154)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352569(CHEMBL1825146 | US8772288, 31)
Affinity DataIC50:  1nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200334((-)-(7S,11S)-huprine H3)
Affinity DataIC50:  1.15nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348319(CHEMBL1800916 | US8772288, 15)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356007(CHEMBL1911342)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200343((-)-(7S,11S)-huprine H7)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352568(CHEMBL1825151)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352571(CHEMBL1825152)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348324(CHEMBL1800910 | US8772288, 3)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352567(CHEMBL1825147 | US8772288, 22)
Affinity DataIC50:  1.65nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352573(CHEMBL1825158)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352574(CHEMBL1825153 | US8772288, 32)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355997(CHEMBL1911332 | US8772288, 63)
Affinity DataIC50:  2nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348322(CHEMBL1800913)
Affinity DataIC50:  2nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352575(CHEMBL1825160)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM10597((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
Affinity DataIC50:  2.77nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348326(CHEMBL1800921)
Affinity DataIC50:  3nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079861((+)-7-fluoro-15-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50:  3.49nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50434452(CHEMBL2385113)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356001(CHEMBL1911336)
Affinity DataIC50:  4nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200340((+/-)-huprine Y-HCl | (+/-)-huprineY hydrochloride...)
Affinity DataIC50:  4.23nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)
Affinity DataIC50:  4.23nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50200336((-)-(7S,11S)-huprine H5)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355998(CHEMBL1911333 | US8772288, 67)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352570(CHEMBL1825154)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50434451(CHEMBL2385124)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at CRTh2 receptor in human eosinophil assessed as inhibition of PGD2-induced cell shape changeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356006(CHEMBL1911341)
Affinity DataIC50:  5nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348325(CHEMBL1800909)
Affinity DataIC50:  5nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352568(CHEMBL1825151)
Affinity DataIC50:  5nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352577(CHEMBL1825145 | US8772288, 29)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352576(CHEMBL1825156 | US8772288, 43)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)
Affinity DataIC50:  5.73nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50348313(CHEMBL1800221 | US8772288, 11)
Affinity DataIC50:  6nMAssay Description:Inhibition of human p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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