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Found 13 with Last Name = 'geyer' and Initial = 'hm'
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  10nMAssay Description:Compound was evaluated for in vitro binding affinity towards Dopamine receptor D2 in rat striatum using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002107(3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for in vitro binding affinity towards serotonin 5-hydroxytryptamine 2 receptor in rat cortex using [3H]- spiperone as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002107(3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin...)
Affinity DataKi:  40nMAssay Description:Compound was evaluated for in vitro binding affinity towards serotonin 5-hydroxytryptamine 1A receptor receptor in rat hippocampus using [3H]-8-OH-D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for in vitro binding affinity towards 5-hydroxytryptamine 2 receptor in rat cortex using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  60nMAssay Description:Compound was evaluated for in vitro binding affinity towards 5-hydroxytryptamine 2 receptor in rat cortex using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002107(3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin...)
Affinity DataKi:  520nMAssay Description:Compound was evaluated for in vitro binding affinity towards Dopamine receptor D2 in rat striatum using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  640nMAssay Description:Compound was evaluated for in vitro binding affinity towards 5-hydroxytryptamine 1A receptor in rat hippocampus using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  790nMAssay Description:Compound was evaluated for in vitro binding affinity towards Dopamine receptor D2 in rat striatum using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002107(3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin...)
Affinity DataKi:  2.74E+3nMAssay Description:Compound was evaluated for in vitro binding affinity towards Dopamine receptor D1 in striatum using [3H]- SCH 23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5.75E+3nMAssay Description:Compound was evaluated for in vitro binding affinity towards 5-hydroxytryptamine 1A receptor in rat hippocampus using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50367064(CHEMBL1204338)
Affinity DataIC50: >1nMAssay Description:Compound was tested in vitro for inhibition of rat brain mitochondrial monoamine oxidase A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50367064(CHEMBL1204338)
Affinity DataIC50: >1nMAssay Description:Compound was tested in vitro for inhibition of rat brain mitochondrial monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50009717(CHEMBL436281)
Affinity DataIC50:  10nMAssay Description:Inhibition of NET-mediated norepinephrine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed