Affinity DataKi: 400nMAssay Description:Compound was tested for inhibition of radioligand [3H]-LTD4 binding to Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataKi: 8.60E+3nMAssay Description:Compound was tested for inhibition of radioligand [3H]-LTC4 binding to Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The compound was tested for the inhibition of binding of [125I]- L- 691,831 binding to 5-lipoxygenase activating proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The compound was tested for the inhibition of binding of [125I]- L- 691,831 binding to 5-lipoxygenase activating protein (FLAP)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:The compound was tested for the inhibition of binding of [125I]- L- 691,831 binding to 5-lipoxygenase activating protein (FLAP)More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:The compound was tested for the inhibition of binding of [125I]- L- 691,831 binding to 5-lipoxygenase activating protein (FLAP)More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:In vitro potency against human 5-LipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human liver CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair