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Found 71 with Last Name = 'gosselin' and Initial = 'g'
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50004352(CHEMBL14925 | [(2R,5S)-5-(6-Amino-purin-9-yl)-tetr...)
Affinity DataKi:  1.20E+5nMAssay Description:inhibitory activity against Adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426318(US10513534, Compound 406)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426319(US10513534, Compound 407)
Affinity DataIC50: <250nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426317(US10513534, Compound 405)
Affinity DataIC50: <250nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426315(US10513534, Compound 403)
Affinity DataIC50: <250nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426312(US10513534, Compound 401)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [S283T](Hepatitis C virus genotype 1b (isolate Japanese) (...)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347266(US10202411, Compound 330)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [S283T](Hepatitis C virus genotype 1b (isolate Japanese) (...)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347265(US10202411, Compound 327)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347265(US10202411, Compound 327)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347259(US10202411, Compound 302)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [S283T](Hepatitis C virus genotype 1b (isolate Japanese) (...)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347259(US10202411, Compound 302)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347260(US10202411, Compound 305)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [S283T](Hepatitis C virus genotype 1b (isolate Japanese) (...)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347260(US10202411, Compound 305)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347262(US10202411, Compound 308)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [S283T](Hepatitis C virus genotype 1b (isolate Japanese) (...)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347262(US10202411, Compound 308)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347266(US10202411, Compound 330)
Affinity DataIC50:  625nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347261(US10202411, Compound 307)
Affinity DataIC50:  625nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347268(US10202411, Compound 332)
Affinity DataIC50:  625nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426314(US10513534, Compound 402)
Affinity DataIC50:  5.50E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347272(US10202411, Compound 402)
Affinity DataIC50:  5.50E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347264(US10202411, Compound 326)
Affinity DataIC50:  5.50E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347263(US10202411, Compound 325)
Affinity DataIC50:  5.50E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347258(US10202411, Compound 301)
Affinity DataIC50:  5.50E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426312(US10513534, Compound 401)
Affinity DataIC50:  6.25E+3nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426315(US10513534, Compound 403)
Affinity DataIC50:  6.25E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426317(US10513534, Compound 405)
Affinity DataIC50:  6.25E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426318(US10513534, Compound 406)
Affinity DataIC50:  6.25E+3nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426319(US10513534, Compound 407)
Affinity DataIC50:  6.25E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426320(US10513534, Compound 408)
Affinity DataIC50:  6.25E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426321(US10513534, Compound 409)
Affinity DataIC50:  6.25E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426322(US10513534, Compound 410)
Affinity DataIC50:  6.25E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426323(US10513534, Compound 411)
Affinity DataIC50:  6.25E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426316(US10513534, Compound 404)
Affinity DataIC50: >1.00E+4nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426316(US10513534, Compound 404)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347271(US10202411, Compound 401)
Affinity DataIC50: >1.00E+4nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347270(US10202411, Compound 335)
Affinity DataIC50: >1.00E+4nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347269(US10202411, Compound 334)
Affinity DataIC50: >1.00E+4nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347267(US10202411, Compound 331)
Affinity DataIC50: >1.00E+4nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285469(3-{[(2S,3R,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-d...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285468({[(2S,3R,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-dih...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA polymerase beta(Homo sapiens (Human))
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50261285(CHEMBL4069349)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-directed RNA polymerase, mitochondrial(Homo sapiens (Human))
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50261285(CHEMBL4069349)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human mitochondrial RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50261285(CHEMBL4069349)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50194151(CHEMBL212090 | [(2R,3S,5S)-5-(2,4-dioxo-3,4-dihydr...)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50194154((2R,3R,4S,5R)-2-(1-(3,4-dihydroxy-5-(diphosphorylo...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50194155((2R,3R,4S,5R)-2-(1-(3,4-dihydroxy-5-(diphosphorylo...)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50179185(((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H...)
Affinity DataEC50:  1.72E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50194156((2R,3R,4S,5R)-4-(benzylthio)-1-(3,4-dihydroxy-5-(d...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50194157(CHEMBL378445 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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