Compile Data Set for Download or QSAR
maximum 50k data
Found 61 with Last Name = 'guindon' and Initial = 'y'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016991(7-Fluoro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  7nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016986(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  11nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofu...)
Affinity DataIC50:  12nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50017001(7-Chloro-2-(2,4-dimethoxy-benzyl)-3-methyl-5-propy...)
Affinity DataIC50:  13nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50017000(5-Allyl-7-chloro-2-(4-methoxy-benzyl)-3-methyl-ben...)
Affinity DataIC50:  20nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016987(7-Chloro-2-(4-methoxy-benzyl)-3,5-dipropyl-benzofu...)
Affinity DataIC50:  20nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016998(7-Chloro-2-(4-chloro-benzyl)-3-methyl-5-propyl-ben...)
Affinity DataIC50:  26nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016994(2-Benzyl-7-chloro-3-methyl-5-propyl-benzofuran-4-o...)
Affinity DataIC50:  30nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016985(2-(4-Methoxy-benzyl)-3-methyl-5-propyl-benzofuran-...)
Affinity DataIC50:  31nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016986(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  36nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016989(7-Chloro-2-(4-methoxy-benzyl)-3,5-dimethyl-benzofu...)
Affinity DataIC50:  46nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016992(7-Chloro-5-(3-hydroxy-propyl)-2-(4-methoxy-benzyl)...)
Affinity DataIC50:  76nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  85nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016997(5-tert-Butyl-7-chloro-2-(4-methoxy-benzyl)-3-methy...)
Affinity DataIC50:  99nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50017002(CHEMBL18559 | [4-(7-Chloro-4-hydroxy-3-methyl-5-pr...)
Affinity DataIC50:  105nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016991(7-Fluoro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  129nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016985(2-(4-Methoxy-benzyl)-3-methyl-5-propyl-benzofuran-...)
Affinity DataIC50:  130nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016990(2-(4-Methoxy-benzyl)-3,7-dimethyl-5-propyl-benzofu...)
Affinity DataIC50:  140nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016992(7-Chloro-5-(3-hydroxy-propyl)-2-(4-methoxy-benzyl)...)
Affinity DataIC50:  161nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016993(7-Chloro-5-ethoxymethyl-2-(4-methoxy-benzyl)-3-met...)
Affinity DataIC50:  291nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016999(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-benzofuran-...)
Affinity DataIC50:  376nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016986(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 5-lipoxygenase reaction catalyzed by purified enzyme from porcine leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016988(2-(4-Methoxy-benzyl)-3-methyl-benzofuran-4-ol | CH...)
Affinity DataIC50:  574nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016996(5,7-Dichloro-2-(4-methoxy-benzyl)-3-methyl-benzofu...)
Affinity DataIC50:  860nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016999(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-benzofuran-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016988(2-(4-Methoxy-benzyl)-3-methyl-benzofuran-4-ol | CH...)
Affinity DataIC50:  2.07E+3nMAssay Description:Concentration required for 50 % inhibition of arachidonic acid oxidation by rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016995(3-[7-Chloro-4-hydroxy-2-(4-methoxy-benzyl)-3-methy...)
Affinity DataIC50:  2.13E+3nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026881(CHEMBL3335530)
Affinity DataIC50:  8.00E+3nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50027066(CHEMBL3335534)
Affinity DataIC50:  8.00E+3nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  9.20E+3nMAssay Description:Concentration required for 50 % inhibition of leukotriene B4 production in human PMN compared with controls in the absence of compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026887(CHEMBL3335533)
Affinity DataIC50:  1.60E+4nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50400720(CHEMBL2204272)
Affinity DataIC50:  1.80E+4nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026870(CHEMBL3335528)
Affinity DataIC50:  1.80E+4nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50400720(CHEMBL2204272)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of immobilized rhPSGL-Ig binding to soluble P-selectin by surface plasmon resonance competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026882(CHEMBL3335531)
Affinity DataIC50:  1.90E+4nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026886(CHEMBL3335532)
Affinity DataIC50:  2.10E+4nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016986(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity of the compound towards soybean lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026871(CHEMBL3335529)
Affinity DataIC50:  3.40E+4nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016986(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of partially purified 15-lipoxygenase from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50016986(7-Chloro-2-(4-methoxy-benzyl)-3-methyl-5-propyl-be...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity of the compound towards porcine 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026881(CHEMBL3335530)
Affinity DataIC50:  6.70E+4nMAssay Description:Antagonist activity at P-selectin (unknown origin) assessed as adhesion to [3H]thymidine-labelled human HL60 cells by static assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026881(CHEMBL3335530)
Affinity DataIC50:  7.60E+4nMAssay Description:Antagonist activity at E-selectin (unknown origin) assessed as adhesion to [3H]thymidine-labelled human HL60 cells by static assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026870(CHEMBL3335528)
Affinity DataIC50:  1.10E+5nMAssay Description:Antagonist activity at P-selectin (unknown origin) assessed as adhesion to [3H]thymidine-labelled human HL60 cells by static assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026870(CHEMBL3335528)
Affinity DataIC50:  1.40E+5nMAssay Description:Antagonist activity at E-selectin (unknown origin) assessed as adhesion to [3H]thymidine-labelled human HL60 cells by static assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026871(CHEMBL3335529)
Affinity DataIC50:  1.90E+5nMAssay Description:Antagonist activity at P-selectin (unknown origin) assessed as adhesion to [3H]thymidine-labelled human HL60 cells by static assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026871(CHEMBL3335529)
Affinity DataIC50:  2.20E+5nMAssay Description:Antagonist activity at E-selectin (unknown origin) assessed as adhesion to [3H]thymidine-labelled human HL60 cells by static assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50026869(CHEMBL3335527)
Affinity DataIC50:  5.20E+5nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50400721(CHEMBL2204273)
Affinity DataIC50:  8.80E+5nMAssay Description:Inhibition of immobilized rhPSGL-Ig binding to soluble P-selectin by surface plasmon resonance competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50400721(CHEMBL2204273)
Affinity DataIC50:  8.80E+5nMAssay Description:Antagonist activity at P-selectin (unknown origin) by surface plasmon resonance-based dynamic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin(Homo sapiens (Human))
Institut De Recherches Cliniques De Montr£Al (Ircm)

Curated by ChEMBL
LigandPNGBDBM50400722(CHEMBL2204274)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of immobilized rhPSGL-Ig binding to soluble P-selectin by surface plasmon resonance competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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