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Found 1279 with Last Name = 'gupta' and Initial = 's'
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.000340nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)
Affinity DataKi:  0.0610nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165019(4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...)
Affinity DataKi:  0.950nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50402408(CHEMBL2203332)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) aggregatesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218053((R)-2-cycloheptyl-2-hydroxy-2-phenyl-N-((1S,5R,6s)...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50131385((2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzen...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109647(2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrro...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM11548(CHEMBL100570 | N-hydroxy-2-[(4-methoxy-1,1-bipheny...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50488953(CHEMBL2296467)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50247674(2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-t...)
Affinity DataKi:  5nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218045((R)-2-cyclohexyl-2-hydroxy-2-phenyl-N-((1S,5R,6s)-...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165017(CHEMBL192485 | Cyclopentyl-hydroxy-phenyl-acetic a...)
Affinity DataKi:  6nMAssay Description:Ki value for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165017(CHEMBL192485 | Cyclopentyl-hydroxy-phenyl-acetic a...)
Affinity DataKi:  6nMAssay Description:Ki value for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218061((R)-N-((1S,5R,6s)-3-benzyl-3-aza-bicyclo[3.1.0]hex...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165008((+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl...)
Affinity DataKi:  6.91nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165019(4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...)
Affinity DataKi:  6.97nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50458333(CHEMBL4210820)
Affinity DataKi:  7nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165008((+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl...)
Affinity DataKi:  7.07nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218043((R)-2-cyclopentyl-2-hydroxy-N-((1S,5R,6s)-3-phenet...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218057((R)-N-((1S,5R,6s)-3-(2-(benzo[d][1,3]dioxol-5-yl)e...)
Affinity DataKi:  12.3nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218051((R)-2-cyclopentyl-2-hydroxy-N-((1S,5R,6s)-3-(4-met...)
Affinity DataKi:  12.4nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50598566(CHEMBL5192359)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) measured by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165012(CHEMBL192065 | Hydroxy-diphenyl-acetic acid 4-(3-a...)
Affinity DataKi:  14nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, liver [T94A](Homo sapiens (Human))
Texas A&M University

LigandPNGBDBM50085042(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
Affinity DataKi:  15nMAssay Description:A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, liver(Homo sapiens (Human))
Texas A&M University

LigandPNGBDBM50085042(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
Affinity DataKi:  15nMAssay Description:A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50109051(CHEMBL330529 | Methyl-[4-(6-methyl-benzothiazol-2-...)
Affinity DataKi:  20nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218058((R)-N-((1S,5R,6s)-3-(2-(benzo[d][1,3]dioxol-5-yl)e...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50458333(CHEMBL4210820)
Affinity DataKi:  20nMAssay Description:Competitive inhibition of human MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH as substrate preincubated for 60 mins followed by substrate addition by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218055((R)-2-cyclopentyl-2-hydroxy-2-phenyl-N-((1S,5R,6s)...)
Affinity DataKi:  25.1nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50342010(5'-phospho-2'-deoxyuridine-3'-pyrophosphate(P'->5'...)
Affinity DataKi:  27nMpH: 5.9Assay Description:Inhibition of bovine pancreatic RNase A at pH 5.9 by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292713(5'-phospho-2'-deoxyuridine 3-pyrophosphate (P'->5'...)
Affinity DataKi:  27nMAssay Description:Inhibition of RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398391(CHEMBL2178602)
Affinity DataKi:  30nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165012(CHEMBL192065 | Hydroxy-diphenyl-acetic acid 4-(3-a...)
Affinity DataKi:  31nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218059((R)-N-((1S,5R,6s)-3-(4-chlorophenethyl)-3-aza-bicy...)
Affinity DataKi:  31.3nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218052((R)-N-((1S,5R,6s)-3-benzyl-3-aza-bicyclo[3.1.0]hex...)
Affinity DataKi:  31.7nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218046((R)-2-cyclopentyl-2-hydroxy-N-((1S,5R,6s)-3-(4-met...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165016(4-Methyl-2-[3-((1R,5S)-2-methyl-3-aza-bicyclo[3.1....)
Affinity DataKi:  34nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165016(4-Methyl-2-[3-((1R,5S)-2-methyl-3-aza-bicyclo[3.1....)
Affinity DataKi:  34nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165010(CHEMBL192537 | Cyclohexyl-hydroxy-phenyl-acetic ac...)
Affinity DataKi:  35nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, liver(Homo sapiens (Human))
Texas A&M University

LigandPNGBDBM119875(3,7,11,15-tetramethylhexadecanoic acid | Phytanic ...)
Affinity DataKi:  35nMAssay Description:A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398394(CHEMBL1232702)
Affinity DataKi:  37nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165017(CHEMBL192485 | Cyclopentyl-hydroxy-phenyl-acetic a...)
Affinity DataKi:  37nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50598556(CHEMBL5174620)
Affinity DataKi:  37nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) aggregatesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFatty acid-binding protein, liver(Rattus norvegicus (Rat))
Texas A&M University

LigandPNGBDBM119875(3,7,11,15-tetramethylhexadecanoic acid | Phytanic ...)
Affinity DataKi:  37nMAssay Description:A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, liver [T94A](Homo sapiens (Human))
Texas A&M University

LigandPNGBDBM119875(3,7,11,15-tetramethylhexadecanoic acid | Phytanic ...)
Affinity DataKi:  38nMAssay Description:A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218053((R)-2-cycloheptyl-2-hydroxy-2-phenyl-N-((1S,5R,6s)...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M2 receptor in rat heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165020(Bis-(4-fluoro-phenyl)-hydroxy-acetic acid 4-(3-aza...)
Affinity DataKi:  39nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165020(Bis-(4-fluoro-phenyl)-hydroxy-acetic acid 4-(3-aza...)
Affinity DataKi:  40nMAssay Description:Affinity for rat Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292721(CHEMBL504858 | [({[(2R,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataKi:  41nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetMuscarinic acetylcholine receptor M3(RAT)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50218047((R)-2-cyclopentyl-2-hydroxy-N-((1S,5R,6s)-3-(napht...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]N-methylscopolamine from muscarinic M3 receptor in rat submandibular glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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