Compile Data Set for Download or QSAR
maximum 50k data
Found 42 with Last Name = 'hackett' and Initial = 'jc'
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9911(3-Phenyl-7-(4-biphenylmethoxy)-2-[(4-pyridylmethyl...)
Affinity DataKi:  39nM ΔG°:  -44.0kJ/mole IC50:  79nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9903(3-Phenyl-7-(beta-naphthylmethoxy)-2-[(4-pyridylmet...)
Affinity DataKi:  74nM ΔG°:  -42.3kJ/mole IC50:  90nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9902(3-Phenyl-7-(alpha-naphthylmethoxy)-2-[(4-pyridylme...)
Affinity DataKi:  114nM ΔG°:  -41.2kJ/mole IC50:  112nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9454(7-(benzyloxy)-3-phenyl-2-[(pyridin-4-ylmethyl)sulf...)
Affinity DataKi:  220nM ΔG°:  -39.5kJ/mole IC50:  210nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9893(2-(1H-Imidazol-1-yl)-3-phenyl-7-(benzyloxy)-4H-1-b...)
Affinity DataKi:  250nM ΔG°:  -39.2kJ/mole IC50:  520nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9459(7-Hydroxy-3-(4-methoxyphenyl)-2-[(4-pyridylmethyl)...)
Affinity DataKi:  260nM ΔG°:  -39.1kJ/mole IC50:  220nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9458(7-Hydroxy-3-(4-hydroxyphenyl)-2-[(4-pyridylmethyl)...)
Affinity DataKi:  310nM ΔG°:  -38.6kJ/mole IC50:  280nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9891(2-(1H-Imidazol-1-yl)-7-methoxy-3-phenyl-4H-1-benzo...)
Affinity DataKi:  680nM ΔG°:  -36.6kJ/mole IC50:  770nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9449(7-Methoxy-3-phenyl-2-[(4-pyridylmethyl)thio]-4H-1-...)
Affinity DataKi:  900nM ΔG°:  -35.9kJ/mole IC50:  1.60E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9452(7-Methoxy-3-(4-methylphenyl)-2-[(4-pyridylmethyl)-...)
Affinity DataKi:  1.16E+3nM ΔG°:  -35.2kJ/mole IC50:  3.00E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50:  2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50:  2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50:  2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9453(7-methoxy-3-(4-methoxyphenyl)-2-[(pyridin-4-ylmeth...)
Affinity DataKi:  1.69E+3nM ΔG°:  -34.3kJ/mole IC50:  3.10E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9892(2-(1H-Imidazol-1-yl)-7-methoxy-3-(4-methoxyphenyl)...)
Affinity DataKi:  1.82E+3nM ΔG°:  -34.1kJ/mole IC50:  2.00E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9894(2-(1H-Imidazol-1-yl)-3-(4-methoxyphenyl)-7-(benzyl...)
Affinity DataKi:  4.40E+3nM ΔG°:  -31.8kJ/mole IC50:  4.70E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  1.20E+4nM ΔG°:  -29.2kJ/mole IC50:  3.40E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  1.20E+4nM ΔG°:  -29.2kJ/mole IC50:  3.40E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9900(3-Phenyl-7-(3-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  113nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9901(3-Phenyl-7-(4-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  132nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9899(3-Phenyl-7-(2-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  138nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9906(3-Phenyl-7-(4-methoxyphenylmethoxy)-2-[(4-pyridylm...)
Affinity DataIC50:  161nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9909(3-Phenyl-7-(4-bromophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  213nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9910(3-Phenyl-7-(4-chlorophenylmethoxy)-2-[(4-pyridylme...)
Affinity DataIC50:  233nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9905(3-Phenyl-7-(2-methoxyphenylmethoxy)-2-[(4-pyridylm...)
Affinity DataIC50:  243nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9908(3-Phenyl-7-(4-fluorophenylmethoxy)-2-[(4-pyridylme...)
Affinity DataIC50:  337nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9904(3-Phenyl-7-(phenylethoxy)-2-[(4-pyridylmethyl)thio...)
Affinity DataIC50:  359nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9912(3-Phenyl-7-(2-pyridylmethoxy)-2-[(4-pyridylmethyl)...)
Affinity DataIC50:  378nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9455(3-(4-Methoxyphenyl)-7-(phenylmethoxy)-2-[(4-pyridy...)
Affinity DataIC50:  530nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9907(3-Phenyl-7-(cyclohexylmethoxy)-2-[(4-pyridylmethyl...)
Affinity DataIC50:  553nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9456(7-Hydroxy-3-phenyl-2-[(4-pyridylmethyl)thio]-4H-1-...)
Affinity DataIC50:  610nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9457(7-Hydroxy-3-phenyl-2-[(3-pyridylmethyl)thio]-4H-1-...)
Affinity DataIC50:  3.60E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9450(7-Methoxy-3-phenyl-2-[(3-pyridylmethyl)thio]-4H-1-...)
Affinity DataIC50:  9.20E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9895(7-Methoxy-3-phenyl-2-(1H-1,2,4-triazol-1-yl)-4H-1-...)
Affinity DataIC50:  1.80E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9897(2-thioazole isoflavone analog 3c | 7-Methoxy-2-(1-...)
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9898(2-thioazole isoflavone analog 3d | 7-Methoxy-3-phe...)
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9896(2-(1H-Imidazolyl-2-thio)-7-methoxy-3-phenyl-4H-1-b...)
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9445(3-(4-Methoxyphenyl)-7-(phenylmethoxy)-2-[(propen-3...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9446(3-(4-Methoxyphenyl)-7-(phenylmethoxy)-2-[(phenylme...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9447(7-Methoxy-3-phenyl-2-[(propen-3-yl)thio]-4H-1-benz...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9448(2-(benzylsulfanyl)-7-methoxy-3-phenyl-4H-chromen-4...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9451(7-Methoxy-3-phenyl-2-[(2-pyridylmethyl)thio]-4H-1-...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed