Compile Data Set for Download or QSAR
maximum 50k data
Found 135 with Last Name = 'hamanaka' and Initial = 'n'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190525((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-methoxybenz...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095207(CHEMBL430154 | [6-(4-Benzhydryl-pyrazol-1-ylmethyl...)
Affinity DataIC50:  8nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284372(CHEMBL11211 | {5-[2-(N',N'-Diphenyl-hydrazinocarbo...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190521(9-(4-allyloxyphenylmethyl)-1-butyl-3-cyclohexyl-1,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81947(CAS_113243-00-8 | L-657926)
Affinity DataIC50:  11nMAssay Description:Binding affinity towards Thromboxane A2/ Prostaglandin H2 receptor in human platelet membranes using [125I]- as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81947(CAS_113243-00-8 | L-657926)
Affinity DataIC50:  11.2nMAssay Description:Binding affinity towards Thromboxane A2/ Prostaglandin H2 receptor in human platelet membranes using [125I]- as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190524(3-(2-methylpropyl)-9-(4-phenoxyphenylmethyl)-1-pro...)
Affinity DataIC50:  17nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284377(CHEMBL11746 | {5-[2-(4-Benzhydryl-pyrazol-1-yl)-et...)
Affinity DataIC50:  18nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190523(1-butyl-9-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)me...)
Affinity DataIC50:  20nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284370(CHEMBL10836 | [6-(N',N'-Diphenyl-hydrazinocarbonyl...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  27nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50452544(CHEMBL2448578)
Affinity DataIC50:  36nMAssay Description:Binding affinity towards Thromboxane A2 receptor/Prostaglandin receptor in human platelet membranes using [125I]- as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)
Affinity DataIC50:  38nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284378(CHEMBL11765 | [6-(4-Benzhydryl-pyrazol-1-ylmethyl)...)
Affinity DataIC50:  40nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50084637(2,2-Dimethyl-propionic acid 4-[2-(carboxymethyl-ca...)
Affinity DataIC50:  44nMAssay Description:Inhibitory concentration of the compound was tested in vitro against Human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM82512(CAS_128719-90-4 | I-BOP)
Affinity DataIC50:  50nMAssay Description:Binding affinity towards Thromboxane A2 receptor/Prostaglandin receptor in human platelet membranes using [125I]- as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190521(9-(4-allyloxyphenylmethyl)-1-butyl-3-cyclohexyl-1,...)
Affinity DataIC50:  50nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50:  83nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190525((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-methoxybenz...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284366((6-{2-[(E)-Benzhydryloxyimino]-butyl}-5,6,7,8-tetr...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095205((6-{2-[(E)-Benzhydryloxyimino]-pentyl}-5,6,7,8-tet...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190523(1-butyl-9-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)me...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  183nMAssay Description:Binding affinity to sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284371(CHEMBL11291 | [5-(2-Benzhydrylideneaminooxy-ethyl)...)
Affinity DataIC50:  210nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284367(((S)-6-{2-[(E)-Benzhydryloxyimino]-propyl}-5,6,7,8...)
Affinity DataIC50:  220nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190515((3R)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284363(((R)-6-{2-[(E)-Benzhydryloxyimino]-propyl}-5,6,7,8...)
Affinity DataIC50:  380nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284374(CHEMBL266622 | [5-(3-Benzhydryloxy-propyl)-5,6,7,8...)
Affinity DataIC50:  460nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190524(3-(2-methylpropyl)-9-(4-phenoxyphenylmethyl)-1-pro...)
Affinity DataIC50:  500nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)
Affinity DataIC50:  560nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284355(CHEMBL10470 | [5-(3-Benzhydryloxyimino-propyl)-5,6...)
Affinity DataIC50:  600nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284355(CHEMBL10470 | [5-(3-Benzhydryloxyimino-propyl)-5,6...)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)
Affinity DataIC50:  610nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284360(CHEMBL10742 | [6-(2-Benzhydryloxyimino-ethyl)-5,6,...)
Affinity DataIC50:  650nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284360(CHEMBL10742 | [6-(2-Benzhydryloxyimino-ethyl)-5,6,...)
Affinity DataIC50:  650nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190515((3R)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)
Affinity DataIC50:  860nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)
Affinity DataIC50:  900nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101853((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284376(CHEMBL11480 | {5-[2-(4-Benzhydryl-pyrazol-1-yl)-et...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190514((3S)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  2.07E+3nMAssay Description:Binding affinity to muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284365((5-{3-[(E)-Benzhydryloxyimino]-hexyl}-5,6,7,8-tetr...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
Displayed 1 to 50 (of 135 total ) | Next | Last >>
Jump to: