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Found 130 with Last Name = 'haraguchi' and Initial = 'h'
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38224(US8546380, 1043 | US8633188, 1043)
Affinity DataIC50:  27nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38224(US8546380, 1043 | US8633188, 1043)
Affinity DataIC50:  27nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38226(US8546380, 1199 | US8633188, 1199)
Affinity DataIC50:  32nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38226(US8546380, 1199 | US8633188, 1199)
Affinity DataIC50:  32nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38220(US8546380, 1100 | US8633188, 1100)
Affinity DataIC50:  37nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38220(US8546380, 1100 | US8633188, 1100)
Affinity DataIC50:  37nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103377(US8546380, 165 | US8633188, 165)
Affinity DataIC50:  39.4nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103377(US8546380, 165 | US8633188, 165)
Affinity DataIC50:  39.4nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38216(US8546380, 739 | US8633188, 739)
Affinity DataIC50:  49nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38216(US8546380, 739 | US8633188, 739)
Affinity DataIC50:  49nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38229(US8546380, 127 | US8633188, 127)
Affinity DataIC50:  54nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38229(US8546380, 127 | US8633188, 127)
Affinity DataIC50:  54nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM34552(US8546380, 793 | US8633188, 793)
Affinity DataIC50:  61nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM34552(US8546380, 793 | US8633188, 793)
Affinity DataIC50:  61nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36793(US8546380, 1244 | US8546380, 1312)
Affinity DataIC50:  130nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36793(US8546380, 1244 | US8546380, 1312)
Affinity DataIC50:  130nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103429(US8546380, 1262 | US8633188, 1262)
Affinity DataIC50:  140nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103429(US8546380, 1262 | US8633188, 1262)
Affinity DataIC50:  140nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103392(US8546380, 570 | US8633188, 570)
Affinity DataIC50:  149nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103392(US8546380, 570 | US8633188, 570)
Affinity DataIC50:  149nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103404(US8546380, 786 | US8633188, 786)
Affinity DataIC50:  156nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103404(US8546380, 786 | US8633188, 786)
Affinity DataIC50:  156nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38222(US8546380, 436 | US8633188, 436)
Affinity DataIC50:  160nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38222(US8546380, 436 | US8633188, 436)
Affinity DataIC50:  160nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38213(US8546380, 96 | US8633188, 96)
Affinity DataIC50:  163nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38213(US8546380, 96 | US8633188, 96)
Affinity DataIC50:  163nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38211(US8546380, 698 | US8633188, 698)
Affinity DataIC50:  165nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM34549(US8546380, 1014 | US8633188, 1014)
Affinity DataIC50:  165nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38211(US8546380, 698 | US8633188, 698)
Affinity DataIC50:  165nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM34549(US8546380, 1014 | US8633188, 1014)
Affinity DataIC50:  165nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38232(US8546380, 1035 | US8633188, 1035)
Affinity DataIC50:  174nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38232(US8546380, 1035 | US8633188, 1035)
Affinity DataIC50:  174nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36406(US8546380, 912 | US8633188, 912)
Affinity DataIC50:  175nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36406(US8546380, 912 | US8633188, 912)
Affinity DataIC50:  175nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36407(US8546380, 212 | US8633188, 212)
Affinity DataIC50:  220nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36407(US8546380, 212 | US8633188, 212)
Affinity DataIC50:  220nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38218(US8546380, 832 | US8633188, 832)
Affinity DataIC50:  222nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38218(US8546380, 832 | US8633188, 832)
Affinity DataIC50:  222nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36405(US8546380, 284 | US8633188, 284)
Affinity DataIC50:  229nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM36405(US8546380, 284 | US8633188, 284)
Affinity DataIC50:  229nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38215(US8546380, 822 | US8633188, 822)
Affinity DataIC50:  243nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38215(US8546380, 822 | US8633188, 822)
Affinity DataIC50:  243nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM34551(US8546380, 964 | US8633188, 964)
Affinity DataIC50:  264nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM34551(US8546380, 964 | US8633188, 964)
Affinity DataIC50:  264nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103387(US8546380, 731 | US8633188, 731)
Affinity DataIC50:  278nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103387(US8546380, 731 | US8633188, 731)
Affinity DataIC50:  278nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38228(US8546380, 73 | US8633188, 73)
Affinity DataIC50:  435nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM38228(US8546380, 73 | US8633188, 73)
Affinity DataIC50:  435nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103413(US8546380, 972 | US8633188, 972)
Affinity DataIC50:  450nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103413(US8546380, 972 | US8633188, 972)
Affinity DataIC50:  450nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
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