Affinity DataKi: 0.00230nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM EC50: 2.00E+3nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of KLK7 (unknown origin) expressed in Pichia pastoris X33 using KHLY-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in sf9 cells using Ac-FVQR-pNA as substrate preincubated for 30 mins followed by substrate addition and...More data for this Ligand-Target Pair
Affinity DataKi: 2nM EC50: 220nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 4nM EC50: 470nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 4nM EC50: 54nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 5nM EC50: 44nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 6nM EC50: 1.20E+3nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 6nM EC50: 43nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVR-pNA as substrate preincubated for 30 mins followed by substrate addition and measured for 7 mins ...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 7nM EC50: 52nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8nM EC50: 1.90E+3nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair