Compile Data Set for Download or QSAR
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Found 31 with Last Name = 'hermans' and Initial = 'e'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080105((3-(1,1-Dimethyl-heptyl)-9-hydroxymethyl-6,6-dimet...)
Affinity DataKi:  0.820nMAssay Description:Ability to displace [3H]-SR- 141716A binding to human CB1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  5.20nMAssay Description:Ability to displace [3H]-SR- 141716A binding to human CB1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  8.90nMAssay Description:Ability to displace [3H]-SR- 141716A binding to human CB1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080103(5,5-Bis-(4-bromo-phenyl)-3-(2-morpholin-4-yl-ethyl...)
Affinity DataKi:  70nMAssay Description:Ability to displace [3H]-SR- 141716A binding to CB1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080102(CHEMBL71810 | JWH-030 | Naphthalen-1-yl-(1-pentyl-...)
Affinity DataKi:  87nMAssay Description:Binding affinity for brain CBI receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080104(5,5-Bis-(4-bromo-phenyl)-3-heptyl-imidazolidine-2,...)
Affinity DataKi:  98nMAssay Description:Ability to displace [3H]-SR- 141716A binding to CB1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080106(5,5-Bis-(4-bromo-phenyl)-3-(3-hydroxy-propyl)-imid...)
Affinity DataKi:  103nMAssay Description:Ability to displace [3H]-SR- 141716A binding to CB1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  152nMAssay Description:Ability to displace [3H]-SR- 141716A binding to human CB1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442711(CHEMBL2442509)
Affinity DataIC50:  10nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  14nMAssay Description:Ability to displace [3H]-SR- 141716A binding to human CB1 receptor expressed in CHO cell membranes in absence of agonist 5''-guanylyimidodiphosphateMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  28nMAssay Description:Ability to displace [3H]-SR- 141716A binding to human CB1 receptor expressed in CHO cell membranes in presence of agonist 5'-guanylyimidodiphosphate ...More data for this Ligand-Target Pair
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442711(CHEMBL2442509)
Affinity DataIC50:  59nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442710(CHEMBL1303766)
Affinity DataIC50:  250nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442718(CHEMBL2442512)
Affinity DataIC50:  730nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442710(CHEMBL1303766)
Affinity DataIC50:  860nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442717(CHEMBL2442515)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442716(CHEMBL2442510)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442715(CHEMBL2442513)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442714(CHEMBL1830821)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442713(CHEMBL2442514)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442712(CHEMBL2442508)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442701(CHEMBL2074836)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442706(CHEMBL2442504)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442709(CHEMBL2442516)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442708(CHEMBL2442517)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442707(CHEMBL2442503)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442702(CHEMBL2442511 | US9296728, 26)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442705(CHEMBL2442505)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442704(CHEMBL2442506)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442703(CHEMBL2442507)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Institut De Recherche Exp£Rimentale Et Clinique (Irec)

Curated by ChEMBL
LigandPNGBDBM50442701(CHEMBL2074836)
Affinity DataIC50:  4.35E+4nMAssay Description:Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed