Compile Data Set for Download or QSAR
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Found 121 with Last Name = 'herron' and Initial = 'dk'
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280290(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity of the compound against human neutrophil ReceptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285071(CHEMBL62051 | sodium 2,4-diethyl-5-[6-methyl-6-(2H...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity of the compound against Guinea pig membrane LTB4 ReceptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036743(CHEMBL60617 | Sodium salt of 4-Ethyl-5-[6-methyl-6...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285072(CHEMBL305560 | sodium 2-butyl-4-ethyl-5-[6-methyl-...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285072(CHEMBL305560 | sodium 2-butyl-4-ethyl-5-[6-methyl-...)
Affinity DataKi:  11nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036743(CHEMBL60617 | Sodium salt of 4-Ethyl-5-[6-methyl-6...)
Affinity DataKi:  14nMAssay Description:Binding affinity against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:Binding affinity against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280286(4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)h...)
Affinity DataKi:  14nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285071(CHEMBL62051 | sodium 2,4-diethyl-5-[6-methyl-6-(2H...)
Affinity DataKi:  17nMAssay Description:Binding affinity against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280286(4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)h...)
Affinity DataKi:  23nMAssay Description:Binding affinity against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280290(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285073(CHEMBL58794 | sodium 4-ethyl-2-hexyl-5-[6-methyl-6...)
Affinity DataKi:  28nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285073(CHEMBL58794 | sodium 4-ethyl-2-hexyl-5-[6-methyl-6...)
Affinity DataKi:  33nMAssay Description:Binding affinity against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,3,4-tet...)
Affinity DataKi:  66nMAssay Description:Binding affinity against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036749(1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,3,4-tet...)
Affinity DataKi:  128nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132988(4-[3-(6-Bromo-pyridin-2-yl)-1H-pyrazol-4-yl]-quino...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132989(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132988(4-[3-(6-Bromo-pyridin-2-yl)-1H-pyrazol-4-yl]-quino...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039472(7-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-phenox...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039467(3-(3-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-phe...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029490(4-Ethyl-5-[6-methyl-6-(1H-tetrazol-5-yl)-heptyloxy...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132986(4-(3-(3-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)q...)
Affinity DataIC50:  6.80nMAssay Description:In vitro inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132989(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Affinity DataIC50:  7.10nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039478(4-Ethyl-2-(1-methyl-1H-pyrazol-3-yl)-5-[6-methyl-6...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039471((3-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-pheno...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039480((2-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-pheno...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132981(4-[5-Methyl-3-(6-methyl-pyridin-2-yl)-1H-pyrazol-4...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132993(4-(3-Phenyl-1H-pyrazol-4-yl)-quinoline | 4-(3-phen...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039475(3-(4-{5-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-phe...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132992(4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenol...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132988(4-[3-(6-Bromo-pyridin-2-yl)-1H-pyrazol-4-yl]-quino...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132992(4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenol...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132989(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Affinity DataIC50:  34nMAssay Description:In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132976(2-[4-(4-Fluoro-phenyl)-1H-pyrazol-3-yl]-6-methyl-p...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132987(2-[4-(4-Methoxy-phenyl)-1-methyl-1H-pyrazol-3-yl]-...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132992(4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenol...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132987(2-[4-(4-Methoxy-phenyl)-1-methyl-1H-pyrazol-3-yl]-...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human Transforming growth factor (TGF) beta-1 receptor (T204D mutation) autophosphorylation in Sf9 cellsMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039477((4-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-pheno...)
Affinity DataIC50:  54nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039469((4-{5-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-pheno...)
Affinity DataIC50:  55nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132994(2-[4-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-6-methyl-p...)
Affinity DataIC50:  57nMAssay Description:In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132987(2-[4-(4-Methoxy-phenyl)-1-methyl-1H-pyrazol-3-yl]-...)
Affinity DataIC50:  61nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132976(2-[4-(4-Fluoro-phenyl)-1H-pyrazol-3-yl]-6-methyl-p...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132980(4-(3-(5-fluoropyridin-2-yl)-1H-pyrazol-4-yl)quinol...)
Affinity DataIC50:  76nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132989(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Affinity DataIC50:  78nMAssay Description:In vitro inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039470(4-{5-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-phenox...)
Affinity DataIC50:  82nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132981(4-[5-Methyl-3-(6-methyl-pyridin-2-yl)-1H-pyrazol-4...)
Affinity DataIC50:  82nMAssay Description:In vitro inhibitory activity against human Transforming growth factor beta-1 receptor kinase (TGF-beta RIK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM81519(CAS_117690-79-6 | CGS 23356 | CHEMBL15766 | LY 255...)
Affinity DataIC50:  85.1nMAssay Description:Inhibition of [3H]-Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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