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Found 154 with Last Name = 'hirohashi' and Initial = 't'
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262553((9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261956(9'-(6-Hydroxy-8-oxospiro[3.5]non-7-yl)-4',9'-dihyd...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262001(9'-(7-Hydroxy-9-oxospiro[4.5]dec-8-yl)-4',9'-dihyd...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261955(9-(4,4-Diethyl-2-hydroxy-6-oxocyclohexyl)-3,3-diet...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262002(9'-(2-Hydroxy-4-oxospiro[5.5]undec-3-yl)-4',9'-dih...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261897(6-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM86733(5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1O...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261898(5-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261724(6-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261899(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3,6-t...)
Affinity DataKi:  36nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261952(6-Bromo-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)...)
Affinity DataKi:  36nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261900(6-Ethyl-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261725(5-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261787(7-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  81nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261721(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-6-metho...)
Affinity DataKi:  93nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261954(9-(2-Hydroxy-4-methyl-6-oxocyclohexyl)-3-methyl-2,...)
Affinity DataKi:  193nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261723(7-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  197nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262552((9R)-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-eny...)
Affinity DataKi:  343nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262555(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-7-metho...)
Affinity DataKi:  590nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261901(6-Ethoxy-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl...)
Affinity DataKi:  833nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262554(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-8-metho...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261953(9-(2-Hydroxy-6-oxocyclohexyl)-2,3,4,9-tetrahydro-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50261722(9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-5-metho...)
Affinity DataKi:  2.17E+3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391002(CHEMBL2074599)
Affinity DataKi:  2.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391002(CHEMBL2074599)
Affinity DataKi:  5.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391003(CHEMBL493586)
Affinity DataKi:  7.70E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from Mrp3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391004(CHEMBL213947)
Affinity DataKi:  8.38E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from Mrp3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 3(Rattus norvegicus)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  9.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from Mrp3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391003(CHEMBL493586)
Affinity DataKi:  1.05E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391004(CHEMBL213947)
Affinity DataKi:  3.37E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetABC-type glutathione-S-conjugate transporter(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  1.20E+6nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicle from MRP3-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258232(1-(Methylsulfonyl)-N-(5-phenylpyrimidin-2-yl)-1,2-...)
Affinity DataIC50:  0.570nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268532(3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzo...)
Affinity DataIC50:  0.670nMAssay Description:Displacement of [125I]PYY from rat NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50298636(1-(Methylsulfonyl)-N-[4-(phenylcarbonyl)phenyl]-1,...)
Affinity DataIC50:  0.680nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268739(CHEMBL524085 | N-(3-(4-chlorophenyl)isoxazol-5-yl)...)
Affinity DataIC50:  0.690nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258191(1-(Methylsulfonyl)-N-(6-phenylpyridin-3-yl)-1,2-di...)
Affinity DataIC50:  0.820nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268737(CHEMBL526084 | N-(3-(2-chlorophenyl)isoxazol-5-yl)...)
Affinity DataIC50:  0.830nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268700(3-oxo-N-(3-phenylisoxazol-5-yl)-3H-spiro[isobenzof...)
Affinity DataIC50:  0.840nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268651(3-oxo-N-(5-(3-(trifluoromethyl)phenyl)pyrimidin-2-...)
Affinity DataIC50:  0.850nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258194(1-(Methylsulfonyl)-N-(2-phenylpyrimidin-5-yl)-1,2-...)
Affinity DataIC50:  0.860nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268534(CHEMBL521545 | N-(5-(3-chlorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  0.910nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258151(1-(Methylsulfonyl)-N-(5-phenylpyridin-2-yl)-1,2-di...)
Affinity DataIC50:  0.960nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258193(1-(Methylsulfonyl)-N-(5-phenylpyrazin-2-yl)-1,2-di...)
Affinity DataIC50:  0.970nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268597(CHEMBL521537 | N-(5-(2-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  0.990nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268738(CHEMBL497621 | N-(3-(3-chlorophenyl)isoxazol-5-yl)...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268594(CHEMBL523060 | N-(5-(2-methoxyphenyl)pyrimidin-2-y...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268533(CHEMBL496196 | N-(5-(2-chlorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268648(CHEMBL495630 | N-(5-(3-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268883(3-oxo-N-(5-phenyl-1,2,4-thiadiazol-3-yl)-3H-spiro[...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50298625(1-(Methylsulfonyl)-N-(3-phenylisoxazol-5-yl)-1,2-d...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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