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Found 90 with Last Name = 'hirschfeld' and Initial = 'dr'
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482300(CHEMBL1170386)
Affinity DataIC50:  14nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482304(CHEMBL1170190)
Affinity DataIC50:  15nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482308(CHEMBL1169643)
Affinity DataIC50:  18nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482304(CHEMBL1170190)
Affinity DataIC50:  19nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482298(CHEMBL1171403)
Affinity DataIC50:  21nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482308(CHEMBL1169643)
Affinity DataIC50:  21nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482299(CHEMBL1170387)
Affinity DataIC50:  22nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482301(CHEMBL1170591)
Affinity DataIC50:  23nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482310(CHEMBL1170006)
Affinity DataIC50:  25nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482301(CHEMBL1170591)
Affinity DataIC50:  27nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482313(CHEMBL1170005)
Affinity DataIC50:  28nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482306(CHEMBL1172334)
Affinity DataIC50:  28nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482300(CHEMBL1170386)
Affinity DataIC50:  28nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482300(CHEMBL1170386)
Affinity DataIC50:  28nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482302(CHEMBL1170378)
Affinity DataIC50:  29nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482299(CHEMBL1170387)
Affinity DataIC50:  30nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482306(CHEMBL1172334)
Affinity DataIC50:  32nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482307(CHEMBL1169811)
Affinity DataIC50:  34nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482301(CHEMBL1170591)
Affinity DataIC50:  37nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482308(CHEMBL1169643)
Affinity DataIC50:  41nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50017914(3-(1-Ethyl-5-pyridin-3-ylmethyl-1H-pyrrol-2-yl)-2-...)
Affinity DataIC50:  42nMAssay Description:Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482302(CHEMBL1170378)
Affinity DataIC50:  43nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50017903(3-(1-tert-Butyl-5-pyridin-3-ylmethyl-1H-pyrrol-3-y...)
Affinity DataIC50:  44nMAssay Description:Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482313(CHEMBL1170005)
Affinity DataIC50:  45nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482307(CHEMBL1169811)
Affinity DataIC50:  50nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50017905(2-Methyl-3-(1-methyl-5-pyridin-3-ylmethyl-1H-pyrro...)
Affinity DataIC50:  50nMAssay Description:Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482302(CHEMBL1170378)
Affinity DataIC50:  62nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482303(CHEMBL1171241)
Affinity DataIC50:  67nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482297(CHEMBL1169982)
Affinity DataIC50:  69nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482304(CHEMBL1170190)
Affinity DataIC50:  70nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482307(CHEMBL1169811)
Affinity DataIC50:  72nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000334(6,7-Dichloro-1,5-dihydro-imidazo[2,1-b]quinazolin-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482310(CHEMBL1170006)
Affinity DataIC50:  84nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482306(CHEMBL1172334)
Affinity DataIC50:  86nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482312(CHEMBL1171331)
Affinity DataIC50:  87nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482298(CHEMBL1171403)
Affinity DataIC50:  90nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482310(CHEMBL1170006)
Affinity DataIC50:  105nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50:  112nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482309(CHEMBL1170018)
Affinity DataIC50:  129nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482297(CHEMBL1169982)
Affinity DataIC50:  131nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482314(CHEMBL1171404)
Affinity DataIC50:  146nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482309(CHEMBL1170018)
Affinity DataIC50:  152nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482314(CHEMBL1171404)
Affinity DataIC50:  159nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50262376(6-((7-(3-chlorobenzyl)benzofuran-5-yl)methyl)pyrid...)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482311(CHEMBL1171516)
Affinity DataIC50:  192nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482298(CHEMBL1171403)
Affinity DataIC50:  208nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482313(CHEMBL1170005)
Affinity DataIC50:  216nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482312(CHEMBL1171331)
Affinity DataIC50:  216nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482315(CHEMBL1171426)
Affinity DataIC50:  229nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482315(CHEMBL1171426)
Affinity DataIC50:  241nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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