Found 68 with Last Name = 'hoffmaster' and Initial = 'k' 
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of FLAP (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 176nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 291nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 296nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 383nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 618nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 785nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 821nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 826nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 853nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 934nMAssay Description:Inhibition of COX2 in human whole blood assessed as LPS-induced PGE2 production incubated 15 mins prior to LPS challenge measured after 24 hrs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of COX2 in dog whole blood assessed as LPS-induced PGE2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7.18E+3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.56E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as PGE2 level incubated for 15 mins prior to substrate addition measured after 10 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PGDSMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
