Affinity DataKi: 190nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Inhibition of FAM-Bid BH3 peptide binding to recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of FAM-Bid BH3 peptide binding to recombinant human BCL2 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+3nMAssay Description:Inhibition of FAM-Bid BH3 peptide binding to recombinant human BCL-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.03E+3nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 2.41E+3nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 3.36E+3nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 4.16E+3nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 6.37E+3nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 6.84E+3nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.08E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.42E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.54E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.58E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.87E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 3.27E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 3.28E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 3.57E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 3.63E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 4.10E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 6.79E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 6.86E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 7.06E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 8.07E+4nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.14E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.66E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.71E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.79E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: 2.16E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) pr...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human N-terminal His-tagged SIRT1 (183 to 664 residues) expressed in Escherichia coli using Ac-Arg-Leu-Ile-Lys(Ac)-AMC as substrate pre...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of c-Kit autophosphorylation in human Kasumi-1 cells by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells by Western blot analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based western blot analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute
Curated by ChEMBL
Industrial Technology Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair