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Found 153 with Last Name = 'ikeda' and Initial = 'h'
TargetCysteine protease ATG4B(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50604041(CHEMBL5200146)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of recombinant ATG4B (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells assessed as inhibition constant using LC3-GST as...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50604040(CHEMBL1358284)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of recombinant ATG4B (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells assessed as inhibition constant using LC3-GST as...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038923(1-[4-(2-Chloro-phenyl)-6,7-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038906(1-[8-Chloro-4-(2-chloro-phenyl)-6-methyl-quinolin-...)
Affinity DataIC50:  8.90nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038918(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  9.20nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038900(1-(7-Chloro-6-methyl-4-o-tolyl-quinolin-3-yl)-3-(2...)
Affinity DataIC50:  9.30nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038920(1-[6-Chloro-4-(2-chloro-phenyl)-8-methyl-quinolin-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038922(1-(2,4-Difluoro-phenyl)-3-(6,8-dimethyl-4-o-tolyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038919(1-[4-(2-Chloro-phenyl)-6-ethyl-quinolin-3-yl]-3-(2...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038905(1-[4-(2-Chloro-phenyl)-6-isopropyl-quinolin-3-yl]-...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038915(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038912(1-[4-(2-Chloro-phenyl)-6-methyl-quinolin-3-yl]-3-(...)
Affinity DataIC50:  16.8nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038901(1-[6-Chloro-4-(2-chloro-phenyl)-quinolin-3-yl]-3-(...)
Affinity DataIC50:  21.2nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038907(1-(2,4-Difluoro-phenyl)-3-(6-methyl-4-o-tolyl-quin...)
Affinity DataIC50:  21.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038916(1-[6-Chloro-4-(2-methoxy-phenyl)-quinolin-3-yl]-3-...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038914(1-[4-(2-Chloro-phenyl)-6,8-dimethyl-quinolin-3-yl]...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038909(1-(6-Chloro-4-o-tolyl-quinolin-3-yl)-3-(2,4-difluo...)
Affinity DataIC50:  28.7nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50604040(CHEMBL1358284)
Affinity DataIC50:  49nMAssay Description:Inhibition of PLA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038913(1-[6-Chloro-4-(3-chloro-phenyl)-quinolin-3-yl]-3-(...)
Affinity DataIC50:  90.6nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194635(US9206129, 51)
Affinity DataIC50:  112nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194589(US9206129, 5)
Affinity DataIC50:  116nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038917(1-[6-Chloro-4-(4-methoxy-phenyl)-quinolin-3-yl]-3-...)
Affinity DataIC50:  121nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038908(1-[4-(2-Chloro-phenyl)-quinolin-3-yl]-3-(2,4-diflu...)
Affinity DataIC50:  125nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194615(US9206129, 31)
Affinity DataIC50:  127nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194629(US9206129, 45)
Affinity DataIC50:  130nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194592(US9206129, 8)
Affinity DataIC50:  136nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194617(US9206129, 33)
Affinity DataIC50:  139nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194601(US9206129, 17)
Affinity DataIC50:  145nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194588(US9206129, 4)
Affinity DataIC50:  149nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038925(1-[4-(2-Chloro-phenyl)-5-methyl-quinolin-3-yl]-3-(...)
Affinity DataIC50:  149nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038910(1-(6-Chloro-4-p-tolyl-quinolin-3-yl)-3-(2,4-difluo...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194637(US9206129, 53)
Affinity DataIC50:  161nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194594(US9206129, 10)
Affinity DataIC50:  170nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194590(US9206129, 6)
Affinity DataIC50:  178nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194593(US9206129, 9)
Affinity DataIC50:  178nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194587(US9206129, 3)
Affinity DataIC50:  188nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194591(US9206129, 7)
Affinity DataIC50:  189nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194596(US9206129, 12)
Affinity DataIC50:  197nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194636(US9206129, 52)
Affinity DataIC50:  212nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50038904(1-(6-Chloro-4-phenyl-quinolin-3-yl)-3-(2,4-difluor...)
Affinity DataIC50:  215nMAssay Description:Inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in rat microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194585(US9206129, 1)
Affinity DataIC50:  229nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194628(US9206129, 44)
Affinity DataIC50:  232nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194618(US9206129, 34)
Affinity DataIC50:  246nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194622(US9206129, 38)
Affinity DataIC50:  250nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194631(US9206129, 47)
Affinity DataIC50:  257nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194606(US9206129, 22)
Affinity DataIC50:  274nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194603(US9206129, 19)
Affinity DataIC50:  287nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194599(US9206129, 15)
Affinity DataIC50:  300nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194605(US9206129, 21)
Affinity DataIC50:  301nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransitional endoplasmic reticulum ATPase(Mus musculus (Mouse))
Daito Chemix

US Patent
LigandPNGBDBM194600(US9206129, 16)
Affinity DataIC50:  304nMpH: 8.0 T: 2°CAssay Description:Mouse VCP cDNA was added with a DNA sequence corresponding to histidine tag at the amino-terminal, subcloned into a baculovirus vector pVL1392 (BD Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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