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Found 24 with Last Name = 'imagire' and Initial = 'js'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009426(2,2-Dimethyl-butyric acid 4-benzylcarbamoyloxy-8-[...)
Affinity DataIC50:  5nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406550(CHEMBL2114188 | CHEMBL3349570)
Affinity DataIC50:  6nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009429(2,2-Dimethyl-butyric acid 4-(diphenyl-phosphinoylo...)
Affinity DataIC50:  6nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009423(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  6nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406549(CHEMBL2115196 | CHEMBL3349562)
Affinity DataIC50:  6.60nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003237(2,2-Dimethyl-butyric acid 2-(1-hydroxy-ethyl)-8-[2...)
Affinity DataIC50:  7.60nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003236(2,2-Dimethyl-butyric acid 2-hydroxymethyl-8-[2-(4-...)
Affinity DataIC50:  11nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003240(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  12nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003240(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  12nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009420(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  13nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003239(2,2-Dimethyl-butyric acid 2-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50:  13nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009422(2,2-Dimethyl-butyric acid 4-dibenzylcarbamoyloxy-8...)
Affinity DataIC50:  16nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003235(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50:  18nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003235(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50:  18nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003241(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  20nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)
Affinity DataIC50:  28nMAssay Description:The compound was tested in vitro for inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009425(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  34nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009418(2,2-Dimethyl-butyric acid 5-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  35nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009419(2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50:  41nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009417(2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50:  49nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009427(2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...)
Affinity DataIC50:  59nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009424(2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydrox...)
Affinity DataIC50:  289nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009421(2,2-Dimethyl-butyric acid 1-(2-{2-[4-(tert-butyl-d...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009428(2,2-Dimethyl-butyric acid 4-hydroxy-1-{6-hydroxy-2...)
Affinity DataIC50:  2.80E+3nMAssay Description:In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed