Affinity DataKi: 0.0600nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of F10a assessed as S-2765 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of F10a assessed as S-2765 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.18nMAssay Description:Binding affinity to TRalpha1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Allosteric inhibition of WNK1 (unknown origin) expressed in HEK293 cells co-expressing flag-OSR1 assessed as reduction in sorbitol-stimulated OSR1 ph...More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Binding affinity to human recombinant mGlur2 assessed as inhibition constant by cAMP Glosensor assayMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 475nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Binding affinity to TRbeta1More data for this Ligand-Target Pair
Affinity DataKi: 1.99E+3nMAssay Description:Displacement of [3H]WIN552122 from human recombinant CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.30E+3nMAssay Description:Inhibitory activity against adenosine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.25E+4nMAssay Description:Binding affinity to TRalpha1More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of thrombin assessed as S-2238 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of activated protein C assessed as S-2366 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of activated protein C assessed as S-2366 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of tPA assessed as S-2288 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of tPA assessed as S-2288 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of plasmin assessed as S-2302 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of thrombin assessed as S-2238 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of plasmin assessed as S-2302 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.45E+4nMAssay Description:Displacement of [3H]WIN552122 from human recombinant CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.45E+4nMAssay Description:Displacement of [3H]WIN552122 from human recombinant CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.64E+4nMAssay Description:Displacement of [3H]WIN552122 from human recombinant CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibitory activity against adenosine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+5nMAssay Description:Inhibitory activity against adenosine deaminaseMore data for this Ligand-Target Pair
TargetPhosphoribosyl pyrophosphate synthase-associated protein 2(Homo sapiens (Human))
Academia Sinica
Curated by ChEMBL
Academia Sinica
Curated by ChEMBL
Affinity DataKi: 7.90E+5nMAssay Description:Inhibitory activity against PRPP synthetaseMore data for this Ligand-Target Pair
Affinity DataKi: >8.00E+5nMAssay Description:Inhibitory activity against adenosine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: >8.00E+5nMAssay Description:Inhibitory activity against adenosine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: >8.00E+5nMAssay Description:Inhibitory activity against adenosine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: >8.00E+5nMAssay Description:Inhibitory activity against adenosine deaminaseMore data for this Ligand-Target Pair
TargetPhosphoribosyl pyrophosphate synthase-associated protein 2(Homo sapiens (Human))
Academia Sinica
Curated by ChEMBL
Academia Sinica
Curated by ChEMBL
Affinity DataKi: 3.00E+6nMAssay Description:Inhibitory activity against PRPP synthetaseMore data for this Ligand-Target Pair
TargetPhosphoribosyl pyrophosphate synthase-associated protein 2(Homo sapiens (Human))
Academia Sinica
Curated by ChEMBL
Academia Sinica
Curated by ChEMBL
Affinity DataKi: 1.70E+7nMAssay Description:Inhibitory activity against PRPP synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD1 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
TargetPlasmepsin II(Plasmodium falciparum)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2More data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD3 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD3 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of FLAG- tagged full length HIF-PHD2 (unknown origin) expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair