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Found 74 with Last Name = 'jeong' and Initial = 'dg'
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253594(1-(3,4-dihydroxyphenyl)-2-[2-(4-methoxyphenyl)-2H-...)
Affinity DataKi:  2.04E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)
Affinity DataKi:  2.14E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)
Affinity DataKi:  2.92E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)
Affinity DataKi:  3.75E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50436447(CHEMBL2397162)
Affinity DataIC50:  800nMAssay Description:Inhibition of human His6-tagged full length PRL3 assessed as inhibition of DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)
Affinity DataIC50:  820nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184297(5-(5-(benzo[b]thiophen-3-yl)-2-(benzyloxy)benzylid...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184288(5-(2-(2-bromobenzyloxy)-5-bromobenzylidene)-2-thio...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184288(5-(2-(2-bromobenzyloxy)-5-bromobenzylidene)-2-thio...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human His6-tagged full length PRL3 assessed as inhibition of DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184287(5-(5-(benzofuran-3-yl)-2-(benzyloxy)benzylidene)-2...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184285(5-(2-(4-bromobenzyloxy)benzylidene)-2-thioxothiazo...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179012(CHEMBL382338 | Sanggenon G)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184298(5-(4-Benzyloxy-biphenyl-3-ylmethylene)-2-thioxo-th...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184296(5-((3-(2-chloro-6-fluorobenzyloxy)naphthalen-2-yl)...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184293(5-[1-[3-(biphenyl-4-ylmethoxy)-naphthalen-2-yl]-me...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184291(5-((3-(benzyloxy)naphthalen-2-yl)methylene)-2-thio...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184290(5-(2-(2-chlorobenzyloxy)-5-bromobenzylidene)-2-thi...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179008(CHEMBL204813 | sanggenon C)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184294(5-(2-(benzyloxy)-5-bromobenzylidene)-2-thioxothiaz...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184292(5-((3-(3,5-dimethoxybenzyloxy)naphthalen-2-yl)meth...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237953(2-(4-allyl-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-y...)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of PRL3 after 1 hr by DiFMUP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184289(5-[1-(4-benzyloxy-4'-dimethylamino-biphenyl-3-yl)-...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184286(5-(2-(benzyloxy)-5-bromobenzyl)-2-thioxothiazolidi...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253594(1-(3,4-dihydroxyphenyl)-2-[2-(4-methoxyphenyl)-2H-...)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)
Affinity DataIC50:  4.27E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50118676(2-(2-Hydroxy-ethylsulfanyl)-3-methyl-[1,4]naphthoq...)
Affinity DataIC50:  4.56E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237953(2-(4-allyl-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-y...)
Affinity DataIC50:  4.67E+3nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179010(CHEMBL378806 | CVD-0019900 | Mulberrofuran C)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253593(2-(3,4-Dimethylphenylamino)-5-(3-furan-2-ylallylid...)
Affinity DataIC50:  5.44E+3nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Affinity DataIC50:  5.49E+3nMAssay Description:Inhibition of Cdc25A (336-523) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50275619(3-benzyl-5-(4-hydroxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of recombinant ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50275622(CHEMBL487154 | N,N'-(1-phenyl-1H-1,2,4-triazole-3,...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of recombinant ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50184295((Z)-5-(5-bromo-2-hydroxybenzylidene)-2-thioxothiaz...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human recombinant PRL-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of VHR DS-PTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50237949(2-(5-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253594(1-(3,4-dihydroxyphenyl)-2-[2-(4-methoxyphenyl)-2H-...)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50275620(3-benzyl-5-(4-hydroxy-3-methoxybenzylidene)-2-thio...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of recombinant ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50237952(3-(2-((1-(3-chlorophenyl)-2,5-dioxoimidazolidin-4-...)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179009(CHEMBL377937 | Kuwanon L)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50275656(5-(4-methylbenzyloxy)-2-(4-phenyl-1H-pyrazol-3-yl)...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of recombinant ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50237948((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50275623(CHEMBL487356 | N-(3-benzamido-1-phenyl-1H-1,2,4-tr...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of recombinant ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM15239(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of recombinant ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50118676(2-(2-Hydroxy-ethylsulfanyl)-3-methyl-[1,4]naphthoq...)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of Cdc25B (378-566) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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