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Found 88 with Last Name = 'jerussi' and Initial = 'tp'
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataIC50:  3.10nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008980(4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl...)
Affinity DataIC50:  5.40nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008982(CHEMBL168723 | N-[4-Methoxymethyl-1-(2-pyrazol-1-y...)
Affinity DataIC50:  10nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM83450(ALFENTANIL | Alfentanil hydrochloride | MLS0023206...)
Affinity DataIC50:  15nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371825(CHEMBL404197)
Affinity DataIC50:  25nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371827(CHEMBL256227)
Affinity DataIC50:  25nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176263(3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycycl...)
Affinity DataIC50:  47nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371815(CHEMBL402116)
Affinity DataIC50:  48nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371815(CHEMBL402116)
Affinity DataIC50:  48nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371832(CHEMBL270642)
Affinity DataIC50:  56nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371814(CHEMBL407563)
Affinity DataIC50:  84nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371831(CHEMBL270570)
Affinity DataIC50:  97nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371826(CHEMBL258140)
Affinity DataIC50:  110nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371824(CHEMBL272063)
Affinity DataIC50:  130nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371822(CHEMBL255768)
Affinity DataIC50:  130nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371828(CHEMBL272533)
Affinity DataIC50:  161nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371833(CHEMBL403388)
Affinity DataIC50:  181nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataIC50:  187nMAssay Description:In vitro binding activity against opioid receptor delta using [3DPDPE] as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371820(CHEMBL257264)
Affinity DataIC50:  190nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371823(CHEMBL270786)
Affinity DataIC50:  190nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371832(CHEMBL270642)
Affinity DataIC50:  525nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008980(4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl...)
Affinity DataIC50:  809nMAssay Description:In vitro binding activity against opioid receptor delta using [3H]-DPDPE) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371818(CHEMBL256163)
Affinity DataIC50:  898nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371828(CHEMBL272533)
Affinity DataIC50:  927nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371833(CHEMBL403388)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371814(CHEMBL407563)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008983(1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371824(CHEMBL272063)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371819(CHEMBL256902)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371820(CHEMBL257264)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371817(CHEMBL258336)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371817(CHEMBL258336)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371829(CHEMBL258338)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008981(CHEMBL169587 | N-{1-[2-(1,3-Dioxo-1,3-dihydro-isoi...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Anaquest

Curated by ChEMBL
LigandPNGBDBM50008982(CHEMBL168723 | N-[4-Methoxymethyl-1-(2-pyrazol-1-y...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro binding activity against opioid receptor delta using [3H]-DPDPE) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371815(CHEMBL402116)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371817(CHEMBL258336)
Affinity DataIC50:  2.59E+3nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371817(CHEMBL258336)
Affinity DataIC50:  2.59E+3nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371816(CHEMBL256371)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371831(CHEMBL270570)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371823(CHEMBL270786)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371817(CHEMBL258336)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371817(CHEMBL258336)
Affinity DataIC50:  2.96E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371816(CHEMBL256371)
Affinity DataIC50:  3.17E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371818(CHEMBL256163)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371822(CHEMBL255768)
Affinity DataIC50:  3.67E+3nMAssay Description:Inhibition of SERT mediated 5-hydroxytryptamine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371824(CHEMBL272063)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50371825(CHEMBL404197)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  3.86E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

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