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Found 27 with Last Name = 'johnstone' and Initial = 'tb'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha-7 nAChR in rat amygdalaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha-7 nAChR in rat hipocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha-7 nAChR in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha-7 nAChR in rat amygdalaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha-7 nAChR in rat hipocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha-7 nAChR in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373060(CHEMBL257155)
Affinity DataEC50:  200nMAssay Description:Activation of human GABAA alpha-2-beta-3-gamma-2L receptor expressed in Xenopus oocytes assessed as modulation of nicotine-induced current by two-ele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441939(CHEMBL2440321)
Affinity DataEC50:  4.90E+3nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441940(CHEMBL2440320)
Affinity DataEC50:  1.20E+3nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441941(CHEMBL2440319)
Affinity DataEC50:  220nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441942(CHEMBL2440317)
Affinity DataEC50:  560nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441943(CHEMBL2440313)
Affinity DataEC50:  210nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441944(CHEMBL2440311)
Affinity DataEC50:  3.00E+3nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441945(CHEMBL2440310)
Affinity DataEC50:  180nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441946(CHEMBL2440308)
Affinity DataEC50:  450nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441947(CHEMBL2440307)
Affinity DataEC50:  130nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441948(CHEMBL2440299)
Affinity DataEC50:  140nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441949(CHEMBL2440298)
Affinity DataEC50:  160nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441950(CHEMBL2440296)
Affinity DataEC50:  380nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441951(CHEMBL2440120)
Affinity DataEC50:  1.90E+3nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataEC50:  6.30E+3nMAssay Description:Activation of human GABAA alpha-2-beta-3-gamma-2L receptor expressed in Xenopus oocytes assessed as modulation of GABA-induced current by two-electro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50373060(CHEMBL257155)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of human alpha-7 nAChR expressed in Xenopus oocytes assessed as modulation of nicotine-induced current by two-electrode voltage-clamp meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataEC50:  500nMAssay Description:Activation of human alpha-7 nAChR expressed in Xenopus oocytes assessed as modulation of nicotine-induced current by two-electrode voltage-clamp meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataEC50:  600nMAssay Description:Activation of human alpha-7 nAChR expressed in Xenopus oocytes assessed as modulation of choline-induced current by two-electrode voltage-clamp metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50441952(CHEMBL2440297)
Affinity DataEC50:  2.50E+3nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50215531(2-chloro-alpha-[[(4-chlorophenyl)amino]methylene]-...)
Affinity DataEC50:  34nMAssay Description:Activity at human GABAA alpha-1-beta-2-gamma-2L expressed in Xenopus oocytes assessed as potentiation of GABA currentsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California Irvine

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataEC50:  700nMAssay Description:Activation of human alpha-7 nAChR expressed in Xenopus oocytes assessed as modulation of acetyl choline -induced current by two-electrode voltage-cla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed