Compile Data Set for Download or QSAR
maximum 50k data
Found 278 with Last Name = 'kahl' and Initial = 'j'
TargetNeutrophil elastase(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50544647(CHEMBL4634122)
Affinity DataKi:  2.96E+3nMAssay Description:Inhibition of human neutrophil elastase using flurogenic substrate as elastase substrate V by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloblastin(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50544646(CHEMBL4635621)
Affinity DataKi:  2.65E+4nMAssay Description:Inhibition of human proteinase 3 using flurogenic substrate as elastase substrate V by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50544646(CHEMBL4635621)
Affinity DataKi:  5.10E+4nMAssay Description:Inhibition of human neutrophil elastase using flurogenic substrate as elastase substrate V by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyeloblastin(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50544648(CHEMBL4636971)
Affinity DataKi:  8.38E+4nMAssay Description:Inhibition of human proteinase 3 using flurogenic substrate as elastase substrate V by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437357(CHEMBL3037909)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of GST-tagged IGF-1R catalytic domain (unknown origin) using omnia Y peptide-12 as substrate assessed as inhibition of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437358(CHEMBL3037908)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of GST-tagged IGF-1R catalytic domain (unknown origin) using omnia Y peptide-12 as substrate assessed as inhibition of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50323659(CHEMBL1208890 | N-(5-tert-butyl-2-methoxy-3-(methy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of phospho-p38 alpha activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50323660(CHEMBL1208891 | N-(5-tert-butyl-2-methoxy-3-(methy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of phospho-p38 alpha activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377234(CHEMBL402902)
Affinity DataIC50:  3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437358(CHEMBL3037908)
Affinity DataIC50:  3nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437357(CHEMBL3037909)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437370(CHEMBL3037912)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377234(CHEMBL402902)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437369(CHEMBL3037913)
Affinity DataIC50:  5nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377237(CHEMBL255735)
Affinity DataIC50:  7nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437358(CHEMBL3037908)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of GST-tagged IGF-1R catalytic domain (unknown origin) using omnia Y peptide-12 as substrate assessed as inhibition of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437367(CHEMBL3037915)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437361(CHEMBL3037921)
Affinity DataIC50:  9nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437362(CHEMBL3037920)
Affinity DataIC50:  9nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377235(CHEMBL402541)
Affinity DataIC50:  9nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50438335(CHEMBL2408610)
Affinity DataIC50:  9nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437368(CHEMBL3037914)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437372(CHEMBL3037910)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437161(CHEMBL2401832)
Affinity DataIC50:  11nMAssay Description:Inhibition of aurora-B (unknown origin) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Affinity DataIC50:  12nMAssay Description:Inhibition of GST-tagged IGF-1R catalytic domain (unknown origin) using omnia Y peptide-12 as substrate assessed as inhibition of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Affinity DataIC50:  13nMAssay Description:Inhibition of GST-tagged IGF-1R catalytic domain (unknown origin) using omnia Y peptide-12 as substrate assessed as inhibition of substrate phosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377237(CHEMBL255735)
Affinity DataIC50:  13nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50323662(CHEMBL1208954 | N-(5-tert-butyl-2-methoxy-3-(methy...)
Affinity DataIC50:  13nMAssay Description:Inhibition of phospho-p38 alpha activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377235(CHEMBL402541)
Affinity DataIC50:  13nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50274366(2-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-N-(4-(2-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50438329(CHEMBL2408616)
Affinity DataIC50:  14nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438335(CHEMBL2408610)
Affinity DataIC50:  15nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437366(CHEMBL3037916)
Affinity DataIC50:  16nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438322(CHEMBL2408612)
Affinity DataIC50:  17nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50438331(CHEMBL2408615)
Affinity DataIC50:  17nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  17nMAssay Description:Inhibition of phospho-p38 alpha activity by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human p38-alpha kinase phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438317(CHEMBL2408611)
Affinity DataIC50:  18nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438329(CHEMBL2408616)
Affinity DataIC50:  20nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50274368(2-(5-tert-butyl-2-methylfuran-3-yl)-N-(4-(6-(morph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human p38alpha phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377240(CHEMBL404565)
Affinity DataIC50:  20nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50323668(CHEMBL1208953 | N-(5-tert-butyl-2-methoxy-3-(methy...)
Affinity DataIC50:  21nMAssay Description:Inhibition of phospho-p38 alpha activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50274367(2-(5-tert-butyl-2-methylfuran-3-yl)-N-(4-(2-morpho...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50323666(CHEMBL1209013 | N-(5-tert-butyl-3-cyano-2-methoxyp...)
Affinity DataIC50:  22nMAssay Description:Inhibition of p38 alpha activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377232(CHEMBL253956)
Affinity DataIC50:  23nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
K£Mia

Curated by ChEMBL
LigandPNGBDBM50374798(CHEMBL255410)
Affinity DataIC50:  23nMAssay Description:Inhibition of human p38-alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Kemia

Curated by ChEMBL
LigandPNGBDBM50377232(CHEMBL253956)
Affinity DataIC50:  23nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437371(CHEMBL3037911)
Affinity DataIC50:  23nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437365(CHEMBL3037917)
Affinity DataIC50:  24nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Affinity DataIC50:  24nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 278 total ) | Next | Last >>
Jump to: