TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 0.75nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]SNAP-7941 from recombinant human MCHR1 expressed in African green monkey COS7 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity of the compound at C-C chemokine receptor type 2 was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of HIV-1 reverse transcriptase incubated for 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.251nMAssay Description:Binding affinity to full-length BRD4 short isoform (unknown origin) by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human BRD4 bromodomain 1/2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human BRD4 bromodomain 1 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human BRD3 bromodomain 1 by BROMOscan assayMore data for this Ligand-Target Pair
TargetBromodomain and PHD finger-containing protein 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of human BRPF3 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.30nMAssay Description:Inhibition of human BRD7 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human BRD3 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human BRD4 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human BRD2 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of human BRPF1 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 14nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibitory activity of the compound against C-C chemokine receptor type 2 (antagonist activity)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli BL21 (DE3) measured after 48 hrs by spectrophotometry analysisMore data for this Ligand-Target Pair
Ligand Info
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand Info
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human cdk2/cyclin E by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of BRDT (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human cdk2/cyclin E by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibitory activity of the compound against C-C chemokine receptor type 2 (antagonist activity)More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand Info
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibitory activity of the compound against C-C chemokine receptor type 2 (antagonist activity)More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand Info
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Dr. Reddys Laboratories
Curated by ChEMBL
Dr. Reddys Laboratories
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Inhibition of human cdk5/p25 by SPAMore data for this Ligand-Target Pair