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Found 92 with Last Name = 'kawakami' and Initial = 'jk'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171394(2-Decyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | CH...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171396(1-((R)-4-Amino-pyrazolo[3,4-d]pyrimidin-2-yl)-deca...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50213599((6aR,10aR)-3-(6-bromo-2-methylhexan-2-yl)-6,6,9-tr...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171395(2-Undecyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | ...)
Affinity DataKi:  0.470nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337798((6aR,10aR)-3-(8-bromo-2-methyloctan-2-yl)-6,6,9-tr...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066705((6R,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-6,9-bis-h...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066705((6R,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-6,9-bis-h...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066709((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066710((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066712((6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxymet...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066706((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-6-(2-hydr...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066712((6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxymet...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066706((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-6-(2-hydr...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066709((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066710((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171393(2-Nonyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | CH...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337797((6aR,10aR)-3-(5-bromopentyl)-6,6,9-trimethyl-6a,7,...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066708((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  9.70nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066707((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-6-ethyl-9...)
Affinity DataKi:  11.1nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066711((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  14.4nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066707((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-6-ethyl-9...)
Affinity DataKi:  21.5nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337796((6aR,10aR)-3-(4-bromobutyl)-6,6,9-trimethyl-6a,7,1...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337799((6aR,10aR)-6,6,9-trimethyl-3-(5,5,5-trifluoropenty...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066711((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  38.9nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 2 from mouse spleen was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
University Of Hawaii

Curated by ChEMBL
LigandPNGBDBM50066708((6S,6aR,9R,10aR)-3-(1,1-Dimethyl-heptyl)-9-hydroxy...)
Affinity DataKi:  40.7nMAssay Description:Binding affinity of the compound to Cannabinoid receptor 1 from rat forebrain synaptosomal membranes was measured using [3H]CP-55,940 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337803(3-(4-amino-2H-pyrazolo[3,4-d]pyrimidin-2-yl)nonan-...)
Affinity DataKi:  53nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337800((6aR,10aR)-9-(fluoromethyl)-6,6-dimethyl-3-pentyl-...)
Affinity DataKi:  103nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337795((6aR,10aR)-6,6,9-trimethyl-3-(octan-2-yl)-6a,7,10,...)
Affinity DataKi:  328nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171387(2-Octyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | CH...)
Affinity DataKi:  530nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50171391(2-Heptyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | C...)
Affinity DataKi:  818nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337801(2-Hexyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | 2-...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337802(2-Dodecyl-2H-pyrazolo[3,4-d]pyrimidin-4-ylamine | ...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorptionChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50337804(5-(7-(benzyloxy)quinazolin-4-ylamino)-4-fluoro-2-m...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption by ELISA assay in presence of 20 uM ATPChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179883((4-Isopropylphenyl)-(4-isoquinolin-5-yl-phthalazin...)
Affinity DataIC50:  17nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM5432(6-(4-methoxyphenyl)-3-(thiophen-3-yl)pyrazolo[1,5-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption by ELISA assay in presence of 20 uM ATPChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataIC50:  45nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179881((4-Chlorophenyl)-(4-isoquinolin-5-yl-phthalazin-1-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179890((4-tert-Butylphenyl)-(4-isoquinolin-5-yl-phthalazi...)
Affinity DataIC50:  75nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50173019(4-(4-(4-tert-butylphenylamino)phthalazin-1-yl)benz...)
Affinity DataIC50:  78nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179889(CHEMBL382818 | N-(4-(chlorodifluoromethoxy)phenyl)...)
Affinity DataIC50:  79nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50173031(4-(4-(4-bromophenylamino)phthalazin-1-yl)benzamide...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179888((3,4-Dichloro-phenyl)-(4-isoquinolin-5-yl-phthalaz...)
Affinity DataIC50:  110nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179891((4-Chloro-3-trifluoromethylphenyl)-(4-isoquinolin-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50173045(4-(4-(4-tert-butylphenylamino)phthalazin-1-yl)-N-m...)
Affinity DataIC50:  130nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50173049(4-(4-(4-(chlorodifluoromethoxy)phenylamino)phthala...)
Affinity DataIC50:  190nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179893((4-Isoquinolin-5-yl-phthalazin-1-yl)-(2-methyl-1Hi...)
Affinity DataIC50:  230nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179884((4-Isoquinolin-5-yl-phthalazin-1-yl)-m-tolylamine ...)
Affinity DataIC50:  270nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179894((4-Isoquinolin-5-yl-phthalazin-1-yl)-(4-morpholin-...)
Affinity DataIC50:  390nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50173022(3-(4-(4-tert-butylphenylamino)phthalazin-1-yl)benz...)
Affinity DataIC50:  400nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu

Curated by ChEMBL
LigandPNGBDBM50179882((2-Fluoro-4-methylphenyl)-(4-isoquinolin-5-ylphtha...)
Affinity DataIC50:  430nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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