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Found 222 with Last Name = 'keiser' and Initial = 'ja'
TargetType-1 angiotensin II receptor A(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82259(CAS_123856 | L-158,809 | NSC_123856)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50009338((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-2-((S)-5-(d...)
Affinity DataKi:  1.60nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-1 angiotensin II receptor A(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50009338((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-2-((S)-5-(d...)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-1 angiotensin II receptor A(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-1 angiotensin II receptor A(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataKi:  12.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM82259(CAS_123856 | L-158,809 | NSC_123856)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by PDSP Ki Database
LigandPNGBDBM50044576(2-Propyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077930(5-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-metho...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077933(4-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-metho...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057169(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phe...)
Affinity DataIC50:  0.120nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077934(3-Benzo[1,3]dioxol-5-yl-4-[3,4-dimethoxy-5-(2-morp...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077935(CHEMBL308646 | {5-[4-Benzo[1,3]dioxol-5-yl-2-hydro...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077936(4-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-metho...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077946(5-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-metho...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057164(CHEMBL10862 | Sodium; (Z)-2-(7-methoxy-benzo[1,3]d...)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077944(CHEMBL408055 | Sodium; 3-{5-[4-benzo[1,3]dioxol-5-...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057150(5-Hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057202(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-3-m...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077941(3-Benzo[1,3]dioxol-5-yl-4-[3,4-dimethoxy-5-(3-morp...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057178(CHEMBL10847 | Sodium; (Z)-2-(7-methoxy-benzo[1,3]d...)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057189(5-Hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4...)
Affinity DataIC50:  0.900nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057166(CHEMBL10922 | Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077943(3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-prop...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057153(CHEMBL10832 | Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057154(CHEMBL10697 | N-{4-[4-Benzo[1,3]dioxol-5-yl-2-hydr...)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057179(3-Benzo[1,3]dioxol-5-yl-4-(3,4-dimethoxy-benzyl)-5...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057181(3-Benzo[1,3]dioxol-5-yl-4-(3,5-dimethoxy-benzyl)-5...)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034259(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-ben...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057167(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phe...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077947(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phe...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077938(3-Benzo[1,3]dioxol-5-yl-4-{3,4-dimethoxy-5-[3-(4-m...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057194(3-Benzo[1,3]dioxol-5-yl-4-(2,5-dimethoxy-benzyl)-5...)
Affinity DataIC50:  2.10nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034269(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-3-m...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077945(3-Benzo[1,3]dioxol-5-yl-4-[3-(2-dimethylamino-etho...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057192(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(3-methoxy-ben...)
Affinity DataIC50:  3nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057207(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phe...)
Affinity DataIC50:  3.90nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057160(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methanesulf...)
Affinity DataIC50:  4nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077942(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phe...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057213(CHEMBL10905 | Potassium; (Z)-3-(4-acetylamino-benz...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057191(4-Benzyl-5-hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5...)
Affinity DataIC50:  6.70nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034256(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-me...)
Affinity DataIC50:  7.40nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057200(3-Benzo[1,3]dioxol-5-yl-4-(2,3-dihydro-benzo[1,4]d...)
Affinity DataIC50:  7.5nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057184(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-hydroxy-ben...)
Affinity DataIC50:  8nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057199(4-Benzyl-5-hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5...)
Affinity DataIC50:  8.20nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077931(CHEMBL70017 | {5-[4-Benzo[1,3]dioxol-5-yl-2-hydrox...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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