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Found 59 with Last Name = 'kennedy' and Initial = 'ja'
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048006(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048004(5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...)
Affinity DataIC50:  270nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50047999(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50:  290nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280281(CHEMBL42593 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2-...)
Affinity DataIC50:  340nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280280(CHEMBL295243 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2...)
Affinity DataIC50:  400nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50230757(CHEMBL301586)
Affinity DataIC50:  510nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280282(CHEMBL295008 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2...)
Affinity DataIC50:  570nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048003(5-[2-(2,3-Dimethyl-phenylamino)-phenyl]-3H-[1,3,4]...)
Affinity DataIC50:  610nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048010(5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...)
Affinity DataIC50:  680nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048005(5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...)
Affinity DataIC50:  690nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048000(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50:  690nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048007(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048007(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...)
Affinity DataIC50:  740nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048004(5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...)
Affinity DataIC50:  770nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)
Affinity DataIC50:  800nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280284(CHEMBL296543 | N-{1-[1-(4-Chloro-benzoyl)-5-methox...)
Affinity DataIC50:  830nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50047998(5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...)
Affinity DataIC50:  850nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50047998(5-(2-(3-(trifluoromethyl)phenylamino)phenyl)-1,3,4...)
Affinity DataIC50:  870nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280279(CHEMBL410500 | N-{1-[1-(4-chlorobenzoyl)-5-methoxy...)
Affinity DataIC50:  890nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048006(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50:  890nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048008(5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048003(5-[2-(2,3-Dimethyl-phenylamino)-phenyl]-3H-[1,3,4]...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50281314(5-(3,5-Di-tert-butyl-4-hydroxy-phenylsulfanyl)-[1,...)
Affinity DataIC50:  1.10E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50281316(2,6-Di-tert-butyl-4-(5-mercapto-[1,3,4]thiadiazol-...)
Affinity DataIC50:  1.10E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280283(CHEMBL46871 | N-[1-(4-Chloro-benzoyl)-5-methoxy-2-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048009(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280279(CHEMBL410500 | N-{1-[1-(4-chlorobenzoyl)-5-methoxy...)
Affinity DataIC50:  1.40E+3nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50281313(2,6-Di-tert-butyl-4-(5-mercapto-[1,3,4]oxadiazol-2...)
Affinity DataIC50:  1.50E+3nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048009(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048002(5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50046918(2,6-Di-tert-butyl-4-[(E)-2-(5-mercapto-[1,3,4]thia...)
Affinity DataIC50:  1.80E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50047999(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50281313(2,6-Di-tert-butyl-4-(5-mercapto-[1,3,4]oxadiazol-2...)
Affinity DataIC50:  2.00E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002435(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was evaluated for the inhibition of serum-opsonized zymosan stimulated LTC4/D4 release from human neutrophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50002435(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was evaluated for the inhibition of serum-opsonized zymosan stimulated LTC4/D4 release from human neutrophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280284(CHEMBL296543 | N-{1-[1-(4-Chloro-benzoyl)-5-methox...)
Affinity DataIC50:  2.40E+3nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048002(5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)
Affinity DataIC50:  2.80E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048008(5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50281315(5-(3,5-Di-tert-butyl-4-hydroxy-phenylsulfanyl)-[1,...)
Affinity DataIC50:  3.10E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50281316(2,6-Di-tert-butyl-4-(5-mercapto-[1,3,4]thiadiazol-...)
Affinity DataIC50:  3.60E+3nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50046918(2,6-Di-tert-butyl-4-[(E)-2-(5-mercapto-[1,3,4]thia...)
Affinity DataIC50:  5.20E+3nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50281315(5-(3,5-Di-tert-butyl-4-hydroxy-phenylsulfanyl)-[1,...)
Affinity DataIC50:  6.00E+3nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048000(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280282(CHEMBL295008 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2...)
Affinity DataIC50:  7.00E+3nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50280280(CHEMBL295243 | N-{[1-(4-chlorobenzoyl)-5-methoxy-2...)
Affinity DataIC50:  7.10E+3nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048010(5-[2-(3-Trifluoromethyl-phenylamino)-phenyl]-[1,3,...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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