TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Affinity for the Corticotropin releasing factor receptor 1 (CRHR1) was determined in rat brainMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Affinity for the Corticotropin releasing factor receptor 1 (CRHR1) was determined in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 5 mins by Kitz-Wilson plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed type inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Non-Competitive inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Reversible inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 5 mins by Kitz-Wilson plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.50E+4nMAssay Description:Reversible inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human JAK1 (866-end residues) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease was evaluatedMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human JAK1 (866-end residues) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory activity of the compound against HIV-1 protease enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant GST-tagged human JAK1 (852 to 1142 residues) using IRS-1 as substrate in presence of 40 uM ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human JAK1 (866-end residues) in presence of ATPMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 3.80nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Tested in vitro for the ability to inhibit HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human JAK1 (866-end residues) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant GST-tagged human JAK2 (809 to 1153 residues) catalytic cytoplasmic domain expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 4.80nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Tested in vitro for the ability to inhibit HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Pseudomonas aeruginosa peptide deformylase after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 5.30nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Tested in vitro for the ability to inhibit HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Pseudomonas aeruginosa peptide deformylase after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Tested in vitro for the ability to inhibit HIV-1 proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 8.30nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Tested in vitro for the ability to inhibit HIV-1 proteaseMore data for this Ligand-Target Pair