Affinity DataKi: 12.2nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 12.8nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 17.3nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 27.8nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 30.6nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 47.2nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 227nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 329nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 770nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in HEK293 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in HEK293 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 15.3nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in HEK293 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University
Curated by ChEMBL
Incheon National University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 28.6nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in HEK293 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair