Compile Data Set for Download or QSAR
maximum 50k data
Found 70 with Last Name = 'king' and Initial = 'sb'
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50095201((S)-2-Amino-5-thioureido-pentanoic acid | 2-Amino-...)
Affinity DataKi:  60nMAssay Description:Compound was tested for the competitive inhibition of nitric oxide synthase (n) using [14C]-L-citrulline as radioligand.; value ranges from 0.06-2 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50095201((S)-2-Amino-5-thioureido-pentanoic acid | 2-Amino-...)
Affinity DataKi:  3.60E+3nMAssay Description:Compound was tested for the competitive inhibition of nitric oxide synthase (i) using [14C]-L-citrulline as radioligand. value ranges from 3.6-9 micr...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077250((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077251((2S)-2-amino-5-{[(1Z)-hydrazino(methylthio)methyle...)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077252((2S)-2-amino-5-[(hydrazinocarbonothioyl)amino]pent...)
Affinity DataKi:  2.02E+5nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295043((E)-12-Nitrooctadec-12-enoic Acid | CHEMBL549351)
Affinity DataIC50:  39nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  130nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50439262(CHEMBL2419244)
Affinity DataIC50:  150nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50:  180nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295044((E)-13-Nitrooctadec-12-enoic Acid | CHEMBL540732)
Affinity DataIC50:  190nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50439263(1-NITROSOCYCLOHEXYL ACETATE)
Affinity DataIC50:  200nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataIC50:  250nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50439264(ANGELI'S SALT | Angeli''s Salt)
Affinity DataIC50:  400nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295045((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid | CHEM...)
Affinity DataIC50:  410nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339180(2-{2-[1-(4-Chlorobenzoyl)-2-methyl-5-methoxyl-1H-i...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339184(CHEMBL1689434 | N-Methoxyl 2-[2-(4-Isobutylphenyl)...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295046((E)-10-Nitrohexadec-9-enoic Acid | CHEMBL564368)
Affinity DataIC50:  630nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50439261(1-NITROSOCYCLOHEXYL TRIFLUOROACETATE)
Affinity DataIC50:  670nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295047((E)-9-Nitrohexadec-9-enoicAcid | CHEMBL560513)
Affinity DataIC50:  830nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295048((E)-9-nitrooctadec-9-enoic acid | CHEMBL550762 | N...)
Affinity DataIC50:  980nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295044((E)-13-Nitrooctadec-12-enoic Acid | CHEMBL540732)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339183(2-[2-(4-Isobutylphenyl)propionoyloxy]ethanesulfony...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295043((E)-12-Nitrooctadec-12-enoic Acid | CHEMBL549351)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295049((E)-10-nitrooctadec-9-enoic acid | CHEMBL561371)
Affinity DataIC50:  1.61E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295050((E)-5-Nitrooctadec-5-enoic Acid | CHEMBL561776)
Affinity DataIC50:  1.68E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295051((E)-6-Nitrooctadec-5-enoic Acid | CHEMBL569372)
Affinity DataIC50:  1.72E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339181((S)-(+)-2-[2-(6-Methoxynaphthyl-2-yl)propionoyloxy...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339181((S)-(+)-2-[2-(6-Methoxynaphthyl-2-yl)propionoyloxy...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077250((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibitory concentration of the compound against mamalian Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295045((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid | CHEM...)
Affinity DataIC50:  9.60E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077250((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339184(CHEMBL1689434 | N-Methoxyl 2-[2-(4-Isobutylphenyl)...)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295046((E)-10-Nitrohexadec-9-enoic Acid | CHEMBL564368)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295048((E)-9-nitrooctadec-9-enoic acid | CHEMBL550762 | N...)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295049((E)-10-nitrooctadec-9-enoic acid | CHEMBL561371)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295051((E)-6-Nitrooctadec-5-enoic Acid | CHEMBL569372)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295050((E)-5-Nitrooctadec-5-enoic Acid | CHEMBL561776)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50295047((E)-9-Nitrohexadec-9-enoicAcid | CHEMBL560513)
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339183(2-[2-(4-Isobutylphenyl)propionoyloxy]ethanesulfony...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50077250((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibitory concentration of the compound against mamalian endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339180(2-{2-[1-(4-Chlorobenzoyl)-2-methyl-5-methoxyl-1H-i...)
Affinity DataIC50:  7.77E+4nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339186(CHEMBL1689435 | Ethanesulfonylhydroxamic Acid)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339182(2-(Phenylacetyloxy)ethanesulfonylhydroxamic Acid |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50339186(CHEMBL1689435 | Ethanesulfonylhydroxamic Acid)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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