Affinity DataKi: 60nMAssay Description:Compound was tested for the competitive inhibition of nitric oxide synthase (n) using [14C]-L-citrulline as radioligand.; value ranges from 0.06-2 mi...More data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Compound was tested for the competitive inhibition of nitric oxide synthase (i) using [14C]-L-citrulline as radioligand. value ranges from 3.6-9 micr...More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
Affinity DataKi: 2.02E+5nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetGlyceraldehyde-3-phosphate dehydrogenase(Oryctolagus cuniculus)
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 1.61E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 1.72E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibitory concentration of the compound against mamalian Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Wake Forest University
Curated by ChEMBL
Wake Forest University
Curated by ChEMBL
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibitory concentration of the compound against mamalian endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.77E+4nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX-1More data for this Ligand-Target Pair