Affinity DataKi: 29nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0430nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0520nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0520nMAssay Description:In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0530nMAssay Description:In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0720nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0720nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0720nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0920nMAssay Description:In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-Sar1-Ile8-AII (without BSA) from type 1 Angiotensin II receptor of rabbit aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT2 receptor from rat midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibitory concentration against AT1 receptor from rat adrenal tissuesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.More data for this Ligand-Target Pair