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Found 123 with Last Name = 'klinge' and Initial = 'd'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050807(3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079431(3-(3,4-Dimethoxy-phenoxy)-2-(4,6-dimethyl-pyrimidi...)
Affinity DataKi:  0.480nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050789(2-(4-Ethyl-6-methyl-pyrimidin-2-yloxy)-3-methoxy-3...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050806(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-d...)
Affinity DataKi:  1nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050796(2-(4,6-Diethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-di...)
Affinity DataKi:  1nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079426(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  1.38nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079432(4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079430(3-[2-(4-Carboxymethoxy-3-methoxy-phenyl)-ethoxy]-2...)
Affinity DataKi:  1.92nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079439(2-(4-Methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-m...)
Affinity DataKi:  1.95nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079438(3-(3,4-Dimethoxy-benzyloxy)-2-(4,6-dimethyl-pyrimi...)
Affinity DataKi:  2nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079424((S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dim...)
Affinity DataKi:  2.15nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079429(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6...)
Affinity DataKi:  2.37nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079435(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-ethoxy-...)
Affinity DataKi:  3.13nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079426(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  3.21nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079423(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-hydroxy...)
Affinity DataKi:  3.48nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079417(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethy...)
Affinity DataKi:  3.49nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079424((S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dim...)
Affinity DataKi:  4.75nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050794(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  6nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079427(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy...)
Affinity DataKi:  6.03nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050802(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-d...)
Affinity DataKi:  7nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079417(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethy...)
Affinity DataKi:  7.15nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050790(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(3-flu...)
Affinity DataKi:  11nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079429(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6...)
Affinity DataKi:  14.7nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079423(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-hydroxy...)
Affinity DataKi:  16.2nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050795(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-diphenyl-3...)
Affinity DataKi:  19nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050810(3-Methoxy-2-(4-methyl-pyrimidin-2-yloxy)-3,3-diphe...)
Affinity DataKi:  19nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079428(3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyr...)
Affinity DataKi:  19.8nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050807(3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  20nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079422(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  20nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  20.4nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050788(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  22nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079421(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  23nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079439(2-(4-Methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-m...)
Affinity DataKi:  23.2nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079430(3-[2-(4-Carboxymethoxy-3-methoxy-phenyl)-ethoxy]-2...)
Affinity DataKi:  24nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050805(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  24nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079427(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy...)
Affinity DataKi:  24.2nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050800(3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyri...)
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079425(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-phenethyloxy-...)
Affinity DataKi:  25nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079435(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-ethoxy-...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050807(3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  29nMAssay Description:Binding affinity of the compound towards Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079419(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  32nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079436(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  32.5nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050797(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-flu...)
Affinity DataKi:  33nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079416(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-3,3-bis-(4-eth...)
Affinity DataKi:  39.3nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079416(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-3,3-bis-(4-eth...)
Affinity DataKi:  40nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079422(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  48nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079436(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  55nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050793(3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapy...)
Affinity DataKi:  56nMAssay Description:Binding affinity of the compound towards Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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