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Found 29 with Last Name = 'klotz' and Initial = 'p'
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151212(CHEMBL2368393 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151218(CHEMBL2368392 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[...)
Affinity DataKi:  8.90nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  23.5nMAssay Description:Displacement of [3H]QNB from EGFP(delta17)human M1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50178133(1-ethyl-2-[(1E,3E)-3-(1-ethylquinolin-2-(1H)-ylide...)
Affinity DataKi:  29.4nMAssay Description:Displacement of [3H]QNB from EGFP(delta17)human M1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151214(CHEMBL2368390 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKi:  45nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50178130(CHEMBL220095 | RR(17)PZ)
Affinity DataKi:  53.5nMAssay Description:Displacement of [3H]QNB from EGFP(delta17)human M1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151215(2-[6-(diethylamino)-3-(diethyliminiumyl)-3H-xanthe...)
Affinity DataKi:  54nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151216(CHEMBL2368391 | difluoro(2-{[(2Z)-1-methyl-5-{2-[(...)
Affinity DataKi:  55nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50178128(Bo(15)PZ | CHEMBL198982)
Affinity DataKi:  69.7nMAssay Description:Displacement of [3H]QNB from EGFP(delta17)human M1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151213(CHEMBL365702 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[5...)
Affinity DataKi:  70nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151219((2E)-2-[(2E)-3-[3,3-dimethyl-1-(5-{[2-(2-{2-[4-(2-...)
Affinity DataKi:  135nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50178129(2-{[4-(diethylamino)phenyl][4-(diethyliminio)cyclo...)
Affinity DataKi:  189nMAssay Description:Displacement of [3H]QNB from EGFP(delta17)human M1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151211(2,2-difluoro-12-[2-(methylcarbamoyl)ethyl]-4-(thio...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151217(CHEMBL2368394 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50178131(6-[(5-carboxypentanoyl)amino]-1-ethyl-2-[(1E,3E)-3...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]QNB from EGFP(delta17)human M1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50178132(CHEMBL370564 | {4-[[4-(5-carboxy-pentylsulfamoyl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]QNB from EGFP(delta17)human M1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione S-transferase kappa 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50422268(GLUTATHIONE | GSH)
Affinity DataIC50:  20nMAssay Description:Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGlutathione S-transferase kappa 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50064878(5-Mercaptomethyl-undecanedioic acid | CHEMBL75497)
Affinity DataIC50:  5.20E+3nMAssay Description:Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione S-transferase kappa 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50064879(5-Mercaptomethyl-decanedioic acid | CHEMBL73552)
Affinity DataIC50:  1.01E+4nMAssay Description:Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione S-transferase kappa 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50064881(4-Mercaptomethyl-decanedioic acid | CHEMBL76285)
Affinity DataIC50:  1.80E+6nMAssay Description:Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151218(CHEMBL2368392 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[...)
Affinity DataKd:  4.10nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKd:  20nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151216(CHEMBL2368391 | difluoro(2-{[(2Z)-1-methyl-5-{2-[(...)
Affinity DataKd:  13nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151214(CHEMBL2368390 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKd:  22nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151219((2E)-2-[(2E)-3-[3,3-dimethyl-1-(5-{[2-(2-{2-[4-(2-...)
Affinity DataKd:  36nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151213(CHEMBL365702 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[5...)
Affinity DataKd:  14nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151212(CHEMBL2368393 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKd:  13nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151215(2-[6-(diethylamino)-3-(diethyliminiumyl)-3H-xanthe...)
Affinity DataKd:  19nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed