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Found 69 with Last Name = 'knobelsdorf' and Initial = 'ja'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071235(CHEMBL65078 | Cyclopropylmethyl-[3-(2,4-dichloro-p...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071234(Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-pyrazo...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071238(3-(2,4-Dichloro-phenyl)-2,5-dimethyl-7-(2-propyl-p...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071229(CHEMBL302645 | [3-(2,4-Dichloro-phenyl)-2,5-dimeth...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071233(Butyl-[3-(2-chloro-phenyl)-2,5-dimethyl-pyrazolo[1...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071226(Butyl-[3-(2,4-dichloro-phenyl)-5-methyl-pyrazolo[1...)
Affinity DataKi:  40nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071232(3-(2,4-Dichloro-phenyl)-2,5-dimethyl-7-piperidin-1...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi:  56nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071228(Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-pyrazo...)
Affinity DataKi:  69nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071237(Butyl-[3-(4-chloro-phenyl)-2,5-dimethyl-pyrazolo[1...)
Affinity DataKi:  77nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071230(Butyl-[2,5-dimethyl-3-(2,4,6-trichloro-phenyl)-pyr...)
Affinity DataKi:  93nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071227(CHEMBL65574 | N-Butyl-N-[3-(2,4-dichloro-phenyl)-2...)
Affinity DataKi:  216nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071236(3-(2,4-Dichloro-phenyl)-2,5-dimethyl-7-morpholin-4...)
Affinity DataKi:  310nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071231(Butyl-(2,5-dimethyl-3-phenyl-pyrazolo[1,5-a]pyrimi...)
Affinity DataKi:  511nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >1.79E+6nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in CHO cells after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >2.40E+6nMAssay Description:Activity at human 5HT1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >2.97E+6nMAssay Description:Activity at human 5HT1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >3.02E+6nMAssay Description:Activity at human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >3.30E+6nMAssay Description:Activity at human 5T2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >3.58E+6nMAssay Description:Activity at human 5HT1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >3.98E+6nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in CHO cells after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >5.37E+6nMAssay Description:Activity at human 5HT1E receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >6.31E+6nMAssay Description:Displacement of human recombinant 5HT4E receptor expressed in CHO cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >6.90E+6nMAssay Description:Displacement of human 5HT5A receptor expressed in HEK293 cells after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >7.47E+6nMAssay Description:Activity at human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >7.87E+6nMAssay Description:Activity at human 5T2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207410(CHEMBL3909995)
Affinity DataIC50:  62nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207406(CHEMBL3890848)
Affinity DataIC50:  74nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207398(CHEMBL3965244)
Affinity DataIC50:  112nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207404(CHEMBL3935529)
Affinity DataIC50:  132nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207411(CHEMBL3973048)
Affinity DataIC50:  144nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207399(CHEMBL3913281)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207405(CHEMBL3918914)
Affinity DataIC50:  203nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207413(CHEMBL3945882)
Affinity DataIC50:  330nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207397(CHEMBL3927834)
Affinity DataIC50:  342nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207403(CHEMBL3911282)
Affinity DataIC50:  346nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207402(CHEMBL3980125)
Affinity DataIC50:  390nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207407(CHEMBL3936830)
Affinity DataIC50:  475nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207412(CHEMBL3920609)
Affinity DataIC50:  484nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207409(CHEMBL3892611)
Affinity DataIC50:  1.43E+3nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207408(CHEMBL3943547)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: >8.00E+3nMAssay Description:Antagonist activity at recombinant human mGlu1 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu5 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207399(CHEMBL3913281)
Affinity DataEC50:  470nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207402(CHEMBL3980125)
Affinity DataEC50:  227nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207405(CHEMBL3918914)
Affinity DataEC50:  319nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu5 expressed in hamster AV12 cells expressing EAAT1 assessed as increase in intracellular calcium level meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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