Affinity DataKi: 0.124nMAssay Description:Binding affinity to rat adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Binding affinity to human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]MSX-2 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to rat adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
Affinity DataKi: 15nM ΔG°: -46.5kJ/molepH: 7.5 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Antagonist activity at rat adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Displacement of [3H]MSX from A2A receptor in rat brain striatum membranes measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Displacement of [3H]CCPA from human A1 receptor expressed in CHO cell membrane by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Displacement of [3H]CCPA from human A1 receptor expressed in CHO cell membrane by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Displacement of [3H]CCPA from A1 receptor in rat brain cortex membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Displacement of [3H]CCPA from rat A1 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >100nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H]CCPA from A1 receptor in rat brain cortex membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 114nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Displacement of [3H]MSX from A2A receptor in rat brain striatum membranes measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 123nM ΔG°: -41.0kJ/molepH: 7.5 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of JNK3 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 135nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 138nMAssay Description:Displacement of [3H]CCPA from A1 receptor in rat brain cortex membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 147nMAssay Description:Binding affinity to rat adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 147nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of [3H]CCPA from A1 receptor in rat brain cortex membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]MSX from A2A receptor in rat brain striatum membranes measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 165nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Displacement of [3H]CCPA from A1 receptor in rat brain cortex membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair
Affinity DataKi: 169nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 187nMAssay Description:Binding affinity to human adenosine A2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
Affinity DataKi: 203nMAssay Description:Displacement of [3H]MSX from human A2A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 217nMAssay Description:Displacement of [3H]MSX from human A2A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 219nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 227nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 228nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [3H]MSX from human A2A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 231nMAssay Description:Displacement of [3H]MSX-2 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 236nMAssay Description:Displacement of [3H]CCPA from human A1 receptor expressed in CHO cell membrane by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 249nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 253nMAssay Description:Displacement of [3H]MSX-2 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 259nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair