Found 872 with Last Name = 'korabecny' and Initial = 'j' TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
University Hospital Hradec Kralove
Curated by ChEMBL
University Hospital Hradec Kralove
Curated by ChEMBL
Affinity DataKi: <0.200nMAssay Description:Binding affinity to ATR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPurchase
Affinity DataKi: 0.300nMAssay Description:Modulation of human D2L receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.456nMAssay Description:Noncompetitive inhibition of human acetylcholinesterase assessed as affinity towards free enzyme using acetylthiocholine iodide as substrate measured...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Modulation of human D2L receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Mixed type inhibition of human erythrocyte AChE assessed as enzyme-substrate-inhibitor complex using varying levels of acetylthiocholine iodide as su...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Mixed type inhibition of human erythrocyte AChE assessed as enzyme-inhibitor complex using varying levels of acetylthiocholine iodide as substrate pr...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
University Hospital Hradec Kralove
Curated by ChEMBL
University Hospital Hradec Kralove
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity to ATR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Mixed inhibition of human butyrylcholinesterase assessed as affinity towards free enzyme using butyrylthiocholine iodide as substrate measured by Ell...More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Non competitive type inhibition of human AChE assessed as inhibition constant using varying levels of acetylthiocholine as substrate by double recipr...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Competitive inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Mixed inhibition of human butyrylcholinesterase assessed as affinity towards enzyme-substrate complex using butyrylthiocholine iodide as substrate me...More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 101nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 225nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 328nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 590nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 770nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 860nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
