TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomesMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Korea Research Institute of Bioscience and Biotechnology
Korea Research Institute of Bioscience and Biotechnology
Affinity DataIC50: 100nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human His6-tagged full length PRL3 assessed as inhibition of DiFMUP dephosphorylationMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of MMP2 expressed in insect cellsMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human His6-tagged full length PRL3 assessed as inhibition of DiFMUP dephosphorylationMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of ACAT expressed in rat liver microsomesMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration of the compound was measured towards partially purified FPTase enzyme from rat brain using a scintillation proximity assay m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of ACAT expressed in rat liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against Acyl-coenzyme A:cholesterol acyltransferase in macrophagesMore data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
University Of Science And Technology
Curated by ChEMBL
University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PRL3 after 1 hr by DiFMUP assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GST-Grb2 Tyrosine kinase SH2 domain binding to [3H]labeled-phosphopeptide (Ac-SpYVNK-NH-C(O)-CH2CH2H3)More data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against Acyl-coenzyme A:cholesterol acyltransferase in macrophagesMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of GST tagged Grb2 SH2 domain (unknown origin) binding to Shc-derived [3H]phosphopeptideMore data for this Ligand-Target Pair
Affinity DataIC50: 5.34E+3nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of GST-Grb2 Tyrosine kinase SH2 domain binding to [3H]labeled-phosphopeptide (Ac-SpYVNK-NH-C(O)-CH2CH2H3)More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibitory activity of compound was measured on rat liver Acyl coenzyme A:cholesterol acyltransferaseMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chungnam National University
Curated by ChEMBL
Chungnam National University
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of STAT3 phosphorylation at Tyr705 residues in human DU145 cells after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Korea Research Institute of Bioscience and Biotechnology
Korea Research Institute of Bioscience and Biotechnology
Affinity DataIC50: 7.50E+3nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of GST-Grb2 Tyrosine kinase SH2 domain binding to [3H]labeled-phosphopeptide (Ac-SpYVNK-NH-C(O)-CH2CH2H3)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Mus musculus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determinedMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chungnam National University
Curated by ChEMBL
Chungnam National University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of STAT3 (unknown origin) expressed in human HCT116 cells after 24 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair