Affinity DataKi: 75.7nMAssay Description:Irreversible inhibition of human MAGL using p-nitrophenylpropionate as substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.331nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 12.3nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 12.3nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 26.3nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 26.3nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Louvain Drug Research Institute
Curated by ChEMBL
Louvain Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FAAH using [3H]anandamide by competitive hydrolysis assayMore data for this Ligand-Target Pair