Affinity DataKi: 0.000350nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.000400nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.00900nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0140nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 6.70nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 6.70nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Binding affinity to recombinant human carbonic anhydrase 2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 7.60nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 7.60nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 7.70nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 7.80nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 8nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 8nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 8nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastricht University Medical Centre
Curated by ChEMBL
Maastricht University Medical Centre
Curated by ChEMBL
Affinity DataKi: 8.10nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair