Affinity DataKi: 6nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5.70E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 7.10E+4nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+5nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataKi: 8.60E+5nMAssay Description:Inhibition of TPPII in rat cererbral membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of steroid sulfatase in human placental microsomes using [3H]E1S as substrate after 30 mins by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 0.120nMpH: 7.4Assay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 0.120nMpH: 7.4 T: 2°CAssay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE® from Perkin Elmer). This c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 0.160nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 0.180nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit
(PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1%
BSA, and 1....More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 0.180nMAssay Description:The phosphodiesterase assay was developed using the LANCE® cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 0.220nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 0.220nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 0.240nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 0.280nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Diaxonhit
US Patent
Diaxonhit
US Patent
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair