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Found 459 with Last Name = 'lee' and Initial = 'gs'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331091(AG-028262 | CHEMBL1289925 | N-methyl-6-(2-(1-methy...)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Src kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331090(4-((5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)methyl...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133707(US8846699, 23)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133709(US8846699, 25)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133696(US8846699, 12)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133702(US8846699, 18)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331083(CHEMBL1290362 | ethyl 2-(3-methyl-7-(3-methylbenzy...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM12255(AZD0530 | CHEMBL217092 | Compound 33 | N-(5-chloro...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Src kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133685(US8846699, 1)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM12255(AZD0530 | CHEMBL217092 | Compound 33 | N-(5-chloro...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Src kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133689(US8846699, 5)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133701(US8846699, 17)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133711(US8846699, 27 | US8846699, 55)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of wild-type EGFR preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331089((S)-3-chloro-N-(4-(2-methyl-3-oxo-3,4-dihydro-2H-b...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133708(US8846699, 24)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133819(US8846699, 137)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50:  4nMAssay Description:Inhibition of HER4 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM5413(1-(2-{4-[3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133713(US8846699, 29)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133697(US8846699, 13)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331088(CHEMBL1290031)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331087(CHEMBL1290137 | N3,N5-bis(4-ethoxyphenyl)-1,2,4-tr...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331081(2-(2-(3-(3-chlorophenyl)ureido)thiazol-4-yl)-N-(6-...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133710(US8846699, 26)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133706(US8846699, 22)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331085(CHEMBL1290247 | N-(3-(2-(4-bromophenylamino)-2-oxo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133803(US8846699, 121)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331084(2-(4-(difluoromethoxy)benzamido)-5-phenylthiophene...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331086(4-((9H-purin-6-ylthio)methyl)-N-(2,5-dimethoxyphen...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133694(US8846699, 10)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133826(US8846699, 144)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133783(US8846699, 101)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133848(US8846699, 168)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133705(US8846699, 21)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133817(US8846699, 135)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133822(US8846699, 140)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133703(US8846699, 19)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133745(US8846699, 61)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133704(US8846699, 20)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50331082(CHEMBL1290361 | N-(2-bromophenyl)-2-(4-(2-methyl-1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133700(US8846699, 16)
Affinity DataIC50:  11nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
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