Affinity DataKi: 0.340nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12.8nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 13.7nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:In vitro binding affinity of the compound was determined against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]-ghrelin ...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 324nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 585nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 643nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 1.67E+3nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.72E+3nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.27E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.94E+3nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.12E+3nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition against recombinant human renin (rHR)More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair