Compile Data Set for Download or QSAR
maximum 50k data
Found 33 with Last Name = 'lemaitre' and Initial = 'a'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316213(4-((3-(2-(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,...)
Affinity DataIC50:  0.400nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316210(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316212(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316205(CHEMBL1096889 | N-(2-(3-(2-(diisopropylamino)ethyl...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316202(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316211(CHEMBL1096895 | N-(2-(3-(4-((diethylamino)methyl)b...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361467(CHEMBL1938400)
Affinity DataIC50:  6nMAssay Description:Inhibition of MINKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233816((2S,3S,4R,5R)-5-(2-((3-(2-(cyclopentyl(isopropyl)a...)
Affinity DataIC50:  6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233816((2S,3S,4R,5R)-5-(2-((3-(2-(cyclopentyl(isopropyl)a...)
Affinity DataIC50:  6nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316209(CHEMBL1096893 | N-(2-(3-benzylureido)ethyl)-6-(2,2...)
Affinity DataIC50:  6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316204(CHEMBL1096888 | N-(2-(3-(2-(cyclopentyl(isopropyl)...)
Affinity DataIC50:  7nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372023(CHEMBL403478)
Affinity DataIC50:  9nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316208(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316206(CHEMBL1096890 | N-(2-(3-(2-(3,4-dihydroisoquinolin...)
Affinity DataIC50:  10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372024(CHEMBL257213)
Affinity DataIC50:  11nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233809((2S,3S,4R,5R)-5-(6-(2,2-diphenylethylamino)-2-((3-...)
Affinity DataIC50:  17nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233809((2S,3S,4R,5R)-5-(6-(2,2-diphenylethylamino)-2-((3-...)
Affinity DataIC50:  17nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361467(CHEMBL1938400)
Affinity DataIC50:  23nMAssay Description:Inhibition of p38beta MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372026(CHEMBL257429)
Affinity DataIC50:  28nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372029(CHEMBL256489)
Affinity DataIC50:  33nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316203(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)te...)
Affinity DataIC50:  45nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372027(CHEMBL270378)
Affinity DataIC50:  60nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233810(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  65nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233810(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  65nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372025(CHEMBL401571)
Affinity DataIC50:  100nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316207(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  305nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361467(CHEMBL1938400)
Affinity DataIC50:  890nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372022(CHEMBL404123)
Affinity DataIC50:  1.00E+3nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372028(CHEMBL404521)
Affinity DataIC50:  1.01E+3nMAssay Description:Agonist activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361467(CHEMBL1938400)
Affinity DataKd:  0.00100nMAssay Description:Binding affinity to human p38alpha MAPK by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361469(CHEMBL1938764)
Affinity DataKd:  3.30nMAssay Description:Binding affinity to p38alpha MAPK by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataKd:  1nMAssay Description:Binding affinity to p38alpha MAPK by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361468(CHEMBL1938736)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to p38alpha MAPK by surface plasmon resonance methodMore data for this Ligand-Target Pair