Affinity DataKi: 88nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
Affinity DataKi: 114nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 6.93E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 8.03E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 8.61E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis)
Katholieke Universiteit Leuven
Curated by ChEMBL
Katholieke Universiteit Leuven
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 770nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 52nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 7.60E+3nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 520nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 860nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 41nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 3.20E+3nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 3.20E+3nMAssay Description:Binding affinity to wild type DNA-tagged human GAK (G13 to Y338 residues) expressed in bacterial expression system by quantitative PCR based KINOMEsc...More data for this Ligand-Target Pair